Exploring the Clinical Impact of MYC Aberrations and Their Relationship With Microenvironment in Diffuse Large B Cell Lymphoma and High-Grade B Cell Lymphoma
NCT06588205 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2025-12-29
Summary
This is a observational, retrospective and prospective study designed to assess the potential correlations between MYC alterations, lymphoma mutational landscape and functional immune contextures in Diffuse Large B-cell Lymphoma or High-Grade B-cell Lymphoma
Conditions
- Diffuse Large B Cell Lymphoma
- High-grade B-cell Lymphoma
- High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements
Sponsors & Collaborators
-
Fondazione Italiana Linfomi - ETS
lead OTHER
Principal Investigators
-
Luisa Lorenzi, MD · SC Anatomia Patologica - ASST Spedali Civili di Brescia
Eligibility
- Min Age
- 18 Years
- Max Age
- 79 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-05-05
- Primary Completion
- 2027-12-31
- Completion
- 2027-12-31
Countries
- Italy
Study Locations
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