Clinical Trials Updated in 2025

NCT07285980 | COMPLETED | NA

180 participants

Comparison of Bier Block and Lidocaine-Propofol Mixture for Prevention of Propofol Injection Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-03-01
Completion:: 2025-07-31

Conditions

Propofol Injection Pain

Interventions

DRUG

No Results Yet

NCT07285967 | NOT_YET_RECRUITING | PHASE1

64 participants

A First-in-Human SAD and MAD Study in Healthy Participants to Evaluate Oral YR011 Tablet

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2026-04-01
Completion:: 2026-09-30

Conditions

Safety
Tolerability
Pharmacokinetics

Interventions

DRUG

No Results Yet

NCT07283848 | WITHDRAWN | PHASE2

0 participants

Zimberelimab + Domvanalimab in Gastroesophageal Adenocarcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2026-02-01
Completion:: 2026-12-01

Conditions

Adenocarcinoma Stomach
Adenocarcinoma Gastroesophageal Junction

Interventions

DRUG

No Results Yet

NCT07282639 | NOT_YET_RECRUITING | NA

99 participants

App-Based Certified Diabetes Education Therapy (AB-CDE)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2026-01-15
Completion:: 2027-05-15

Conditions

Type 1 Diabetes (T1D)

Interventions

DEVICE

No Results Yet

NCT07279077 | RECRUITING | PHASE2

38 participants

Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-11-26
Completion:: 2030-11-25

Conditions

Colon Cancer
Neoadjuvant Therapies
Immune Checkpoint Therapy
Radiation Therapy

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07274254 | NOT_YET_RECRUITING | PHASE3

104 participants

Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2026-03-01
Completion:: 2028-03-01

Conditions

Vaso-Occlusive Pain Episode in Sickle Cell Disease

Interventions

DRUG

No Results Yet

NCT07270263 | RECRUITING | NA

100 participants

Reduced-Dose Apixaban and Rivaroxaban Versus Low-Molecular-Weight Heparin in Patients With Hematologic Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2024-11-22
Completion:: 2026-04-30

Conditions

Lymphoma
Leukemia
Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma
Venous Thromboembolic Disease
VTE (Venous Thromboembolism)
PE - Pulmonary Embolism
Hematologic Malignacies

Interventions

DRUG

No Results Yet

NCT07270224 | COMPLETED

52 participants

Motor Imagery, Hand Mental Rotation, and Performance in Female Volleyball Players

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-11-10
Completion:: 2025-11-25

Conditions

Motor Imagery
Volleyball
Reaction Time
Vertical Jump Performance

No Results Yet

NCT07267260 | RECRUITING | PHASE2

154 participants

Evaluating the Efficacy of Vonoprazan in Preventing Post-Endoscopic Variceal Band Ligation Ulcers: A Randomized Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-12-16
Completion:: 2026-01-30

Conditions

Cirrhoses, Liver

Interventions

DRUG
OTHER

No Results Yet

NCT07263139 | RECRUITING | PHASE2

10 participants

Safety, Tolerability, and Exploratory Efficacy of AGP100 in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2026-01-02
Completion:: 2027-06-30

Conditions

Catecholaminergic Polymorphic Ventricular Tachycardia

Interventions

DRUG

No Results Yet

NCT07256652 | RECRUITING | NA

100 participants

How Does YES Bar Affect Blood Glucose Levels?

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-08-25
Completion:: 2026-08-25

Conditions

Blood Glucose Monitoring

Interventions

OTHER

No Results Yet

NCT07256639 | RECRUITING | NA

100 participants

Evaluating Heart & Soil's Whole Package on Men's Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-10-17
Completion:: 2026-10-17

Conditions

Testosterone

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07256626 | ENROLLING_BY_INVITATION | NA

100 participants

Tune Up Your Back: Soundwave Wellness Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-08-25
Completion:: 2026-08-25

Conditions

Pain, Back

Interventions

DEVICE

No Results Yet

NCT07256574 | ENROLLING_BY_INVITATION | NA

100 participants

Sun-Kissed Serenity: Morning Rays for a Brighter Mind

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-09-11
Completion:: 2026-09-30

Conditions

Mental Status Change

Interventions

BEHAVIORAL

No Results Yet

NCT07243119 | ENROLLING_BY_INVITATION | PHASE4

180 participants

PRIMA-HF: Predicting Myocardial Recovery in Heart Failure Using Cardiac Imaging HAI-HF: High Dosing vs. Standard Dosing Adenosine During Myocardial Perfusion in Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-12-08
Completion:: 2029-04-30

Conditions

Heart Failure and Reduced Ejection Fraction
Heart Failure

Interventions

DIAGNOSTIC_TEST
DRUG

No Results Yet

NCT07240636 | RECRUITING | PHASE1

16 participants

Study of Food Effects of VV119 Capsules in Chinese Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-11-28
Completion:: 2026-10-31

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT07230639 | RECRUITING | PHASE2

52 participants

Node-Sparing Hypofractionated Radiotherapy Plus Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Randomized, Phase II Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-08-30
Completion:: 2030-08-29

Conditions

Neoadjuvant Therapies
Immune Checkpoint Therapy
Radiotherapy

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07229391 | NOT_YET_RECRUITING | NA

60 participants

Behavior Therapy vs Education for Persistent Headache After Mild TBI

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2027-10-01
Completion:: 2030-01-01

Conditions

Post-Traumatic Headache

Interventions

BEHAVIORAL

No Results Yet

NCT07225959 | ACTIVE_NOT_RECRUITING | PHASE2

400 participants

A Study to Evaluate the Safety, Pharmacokinetics, and Occurrence of Anti-Drug Antibodies Following Annual Doses of CD388

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-10-29
Completion:: 2027-07-31

Conditions

Healthy Participants

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT07216469 | RECRUITING

20 participants

A Study Of Myocardial Stiffness In Amyloidosis With Magnetic Resonance Elastography

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-10-14
Completion:: 2027-11-30

Conditions

Amyloidosis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07203768 | RECRUITING

678 participants

A ELN-Multicenter Study on Phenotypic Evolution and Clinical Outcomes

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-12-01
Completion:: 2026-04-30

Conditions

Polycythemia Vera
Thrombocythemia

No Results Yet

NCT07190170 | RECRUITING | NA

110 participants

Time Restricted Eating for WeIght LoSs MainTenance-2

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-10-01
Completion:: 2028-01-01

Conditions

Weight Loss
Weight Gain
Weight Loss Maintenance

Interventions

BEHAVIORAL

No Results Yet

NCT07188844 | ENROLLING_BY_INVITATION | PHASE2

108 participants

An Open-Label Extension Study of Batoclimab in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-08-28
Completion:: 2028-11-30

Conditions

Chronic Inflammatory Demyelinating Polyneuropathy

Interventions

DRUG

No Results Yet

NCT07179393 | COMPLETED | NA

197 participants

Evaluating the Efficacy of a Ladies Gaelic Football-Specific Injury Prevention Programme

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-06-23
Completion:: 2025-10-03

Conditions

Injury
Physical Performances

Interventions

BEHAVIORAL

No Results Yet

NCT07167628 | COMPLETED

274 participants

Neurological Complications and ICU Workload After Emergency Repair of Acute Type A Aortic Dissection

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-26
Start Date:: 2021-01-01
Completion:: 2025-04-30

Conditions

Coma
Delirium
Aortic Dissection
Stroke
Paraplegia
AKI - Acute Kidney Injury

No Results Yet

NCT07154472 | COMPLETED

32 participants

Upper Limb Function in Paraplegic Individuals: Exploring Endurance, Performance, and Symptoms

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-01-15
Completion:: 2025-10-08

Conditions

Paraplegia
Endurance
Symptoms

No Results Yet

NCT07143942 | COMPLETED | NA

42 participants

Effects of Kinesio Taping on Gait Biomechanics in Patellar Tendinopathy Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-08-31
Completion:: 2025-12-01

Conditions

Patellar Tendinopathy / Jumpers Knee
Kinesio Taping

Interventions

BEHAVIORAL

No Results Yet

NCT07127965 | RECRUITING | NA

226 participants

Exercise Adherence and Cognitive Decline: Phase 2

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-11-05
Completion:: 2028-08-31

Conditions

Cognitive Decline

Interventions

BEHAVIORAL

No Results Yet

NCT07077005 | RECRUITING | NA

24 participants

Mavacamten Enables Exercise in Hypertrophic Obstructive Cardiomyopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-11-01
Completion:: 2026-10-31

Conditions

Cardiomyopathy, Hypertrophic

Interventions

OTHER

No Results Yet

NCT07052266 | RECRUITING | NA

550 participants

Trial of Combined Obstetric Carrier Screening and Hereditary Cancer Screening

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-09-02
Completion:: 2027-06-30

Conditions

Hereditary Cancer Syndromes

Interventions

GENETIC

No Results Yet

NCT07040475 | RECRUITING

2500 participants

Effects of the Clinical Application of Traditional, Complementary and Integrative Medicine (TCIM) Procedures During Inpatient Stays in Germany

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-07-01
Completion:: 2026-12-31

Conditions

Chronic Disease

Interventions

OTHER

No Results Yet

NCT07039864 | COMPLETED | NA

100 participants

A Novel Strategy for Evaluating Gallbladder Contraction Function by Ultrasound

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-06-26
Completion:: 2025-12-20

Conditions

Gallbladder; Functional Disturbance

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07031076 | WITHDRAWN | NA

0 participants

Investigating the Cognitive and Brain Health Benefits of Lean Pork Consumption

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-08-31
Completion:: 2026-12-31

Conditions

Dietary Intervention
Dietary Proteins
Dietary Assessment
Older Adults (65 Years and Older)
Cognitive Ability, General

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07022938 | COMPLETED | PHASE4

71 participants

Nutritional Supplement for Treating Chemotherapy Induced Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2021-11-01
Completion:: 2025-01-31

Conditions

Cancer
Neuropathy
Chemotherapy Induced Pain Neuropathy
Chemotherapy-Induced Peripheral Neuropathy

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT07007117 | RECRUITING | PHASE1

38 participants

PHOX2B PC-CAR T Cells for Relapsed Neuroblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-06-20
Completion:: 2032-06-30

Conditions

Refractory Neuroblastoma
Relapsed Neuroblastoma
High-Risk Neuroblastoma

Interventions

BIOLOGICAL

No Results Yet

NCT07003906 | RECRUITING | NA

720 participants

Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-12-16
Completion:: 2028-12-31

Conditions

Surgical Incision
Wound Dehiscence
Surgical Site Infection
Incisional Hernia
Quality of Life

Interventions

DEVICE

No Results Yet

NCT06992037 | COMPLETED

1110 participants

An Ambispective Registry Study Comparing Clinical Outcomes of Surgical Interventions for the Treatment of Nasal Airway Obstruction.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-03-14
Completion:: 2025-07-21

Conditions

Nasal Airway Obstruction

No Results Yet

NCT06991101 | RECRUITING | PHASE2

190 participants

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-12-03
Completion:: 2030-12-31

Conditions

Glioblastoma
Brain Cancer
Glioblastoma Multiforme
Glioblastoma Multiforme of Brain
Glioblastoma Multiforme, Adult
MGMT-Unmethylated Glioblastoma
MGMT-Methylated Glioblastoma

Interventions

DRUG
RADIATION

No Results Yet

NCT06975020 | RECRUITING | NA

120 participants

Pilot-Study for the Comparison of Biomarkers Between Regular Cannabis Users and Non-Users

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-12-19
Completion:: 2026-12-31

Conditions

Driving Under the Influence of Cannabis

Interventions

DRUG

No Results Yet

NCT06958744 | COMPLETED | NA

40 participants

Effects of Functional Inspiratory Muscle Training in Patients With Chronic Non-Specific Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-26
Start Date:: 2025-04-30
Completion:: 2025-09-17

Conditions

Low Back Pain

Interventions

OTHER

No Results Yet