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Treating Emergency Laparotomy Incisions With Negative Pressure Wound Therapy

NCT07003906 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 720

Last updated 2025-12-26

No results posted yet for this study

Summary

The goal of this clinical trial is to investigate Negative Pressure Wound Therapy (NPWT) in adults undergoing emergency laparotomy. The main question it aims to answer is:

Does NPWT decrease wound complications?

Researchers will compare it against regular dressings to see if NPWT is superior.

Conditions

  • Surgical Incision
  • Wound Dehiscence
  • Surgical Site Infection
  • Incisional Hernia
  • Quality of Life

Interventions

DEVICE

Negative pressure wound therapy

Avance Solo Negative Pressure Wound Therapy (NPWT) System is a portable battery powered single use negative pressure system, suitable for use in closed incision and chronic wound indications. The system consists of Avance Solo Pump, Avance Solo Canister 50 mL, Avance Solo Border Dressing and Avance Solo Foam.

DEVICE

Standard postoperative dressing

Mepilex Border Post-Op is a self-adhesive absorbent surgical dressing designed for exuding wounds. It is intended for acute wounds, such as surgical wounds, cuts and abrasions.

Sponsors & Collaborators

  • Uppsala County Council, Sweden

    collaborator OTHER_GOV

  • Dalarna County Council, Sweden

    collaborator OTHER

  • Sormland County Council, Sweden

    collaborator OTHER

  • Ostergotland County Council, Sweden

    collaborator OTHER

  • Västmanland County Council, Sweden

    collaborator OTHER_GOV

  • Landstingens Ömsesidiga Försäkringsbolag (Löf)

    collaborator UNKNOWN

  • Uppsala University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-16
Primary Completion
2028-12-31
Completion
2035-12-31

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07003906 on ClinicalTrials.gov