Clinical Trials Updated in 2025

NCT06410443 | RECRUITING | NA

60 participants

Efficacy and Safety of Local Glucocorticoids for the Treatment of Acute Radiation-Induced Intestinal Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-08-01
Completion:: 2026-12-31

Conditions

Radiation-Induced Intestinal Injury

Interventions

DRUG

No Results Yet

NCT06404437 | ACTIVE_NOT_RECRUITING

100 participants

Detection of Aortic Stenosis With Smartphone Auscultation Using Machine Learning (HEARTBEAT-Pilot)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-03-09
Completion:: 2024-05-22

Conditions

Aortic Valve Stenosis

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06395506 | RECRUITING | NA

60 participants

THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-10-29
Completion:: 2028-05-31

Conditions

Breast Cancer
Breast Cancer Female
Muscle Weakness

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06376123 | COMPLETED

40 participants

Nomogram for Prediction of Alveolo-arterial Gradient During One-lung Ventilation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-06-01
Completion:: 2024-11-01

Conditions

One-lung Ventilation

No Results Yet

NCT06365216 | ACTIVE_NOT_RECRUITING | PHASE2

80 participants

ALS Phase II Study of NX210c

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-10-25
Completion:: 2026-02-01

Conditions

Amyotrophic Lateral Sclerosis

Interventions

DRUG

No Results Yet

NCT06347588 | ACTIVE_NOT_RECRUITING

60 participants

Risk of Reactivation of Occult Hepatitis B in Cancer Patients During Immunotherapy.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2022-06-06
Completion:: 2026-05-31

Conditions

Occult Hepatitis B Infection in Cancer Patients

Interventions

OTHER

No Results Yet

NCT06328673 | ACTIVE_NOT_RECRUITING | PHASE1

160 participants

A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-04-09
Completion:: 2026-03-01

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT06321718 | COMPLETED | NA

96 participants

Pericapsular Nerve Group Block vs Supra Inguinal Fascia Iliaca Compartment Block

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-05-01
Completion:: 2025-11-01

Conditions

Pain, Postoperative

Interventions

PROCEDURE

No Results Yet

NCT06321094 | COMPLETED

149 participants

Effect of Vericiguat on Acute Coronary Syndrome( ACS）Patients With Ejection Fraction <45%

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-01-31
Completion:: 2025-10-01

Conditions

Acute Coronary Syndrome
Heart Failure With Reduced Ejection Fraction

No Results Yet

NCT06293521 | RECRUITING | PHASE2

40 participants

Clinical and Radiographic Success Rate of Pulpotomy Versus Pulpectomy for Management of Primary Teeth With Deep Caries

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2026-01-01
Completion:: 2026-01-31

Conditions

Deep Caries

Interventions

PROCEDURE

No Results Yet

NCT06292000 | WITHDRAWN | NA

0 participants

Examining the Effects of Morning and Evening Exercise on Glucose Regulation in Adults With Prediabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-02-01
Completion:: 2026-06-30

Conditions

PreDiabetes
Obesity
Inactivity/Low Levels of Exercise

Interventions

BEHAVIORAL

No Results Yet

NCT06275087 | RECRUITING | NA

42 participants

Differences in Speed of Recovery From Anesthesia for Intraoral Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-04-10
Completion:: 2025-11-05

Conditions

Intraoral Tumor

Interventions

DRUG

No Results Yet

NCT06256380 | RECRUITING | NA

200 participants

Comparing Enhanced Cognitive-behavior Therapy and Family-based Treatment for Adolescents With an Eating Disorder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-03-07
Completion:: 2028-12-31

Conditions

Feeding and Eating Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06238544 | ACTIVE_NOT_RECRUITING | PHASE2

132 participants

Long-term Safety and Tolerability of HRS-5965 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-02-06
Completion:: 2027-12-31

Conditions

Paroxysmal Nocturnal Hemoglobinuria

Interventions

DRUG

No Results Yet

NCT06218134 | COMPLETED | NA

3 participants

Evaluate the Safety and Potential Efficacy of Human Wharton's Jelly-derived Mesenchymal Stem Cells With Charcot-Marie-Tooth Disease Type 1E

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-05-23
Completion:: 2024-10-28

Conditions

Charcot-Marie-Tooth Disease, Type 1

Interventions

BIOLOGICAL

No Results Yet

NCT06211634 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

57 participants

A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2022-12-13
Completion:: 2027-08-31

Conditions

Glanzmann Thrombasthenia

Interventions

DRUG

No Results Yet

NCT06204887 | COMPLETED | NA

97 participants

Effect of Irrigation-Activation Techniques on Healing in Large Periapical Lesions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2021-11-01
Completion:: 2023-02-27

Conditions

Effect of Irrigation Activation on Periapical Healing

Interventions

PROCEDURE

Results Available

NCT06188481 | COMPLETED | NA

66 participants

Efficacy of Whole-body Electromyostimulation (WB-EMS) Training in Participants With Pre-diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-01-23
Completion:: 2025-12-17

Conditions

Pre-diabetes

Interventions

OTHER

No Results Yet

NCT06184126 | RECRUITING | NA

30 participants

Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-11-01
Completion:: 2026-09-30

Conditions

Sickle Cell Disease
Vaso-occlusive Pain Episode in Sickle Cell Disease
Acute Pain

Interventions

DEVICE
OTHER

No Results Yet

NCT06147258 | RECRUITING | NA

60 participants

The Impact of Expressive Emotional Writing on Facilitating Grief Resolution in Adults With Spinal Cord Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-05-03
Completion:: 2026-12-31

Conditions

Spinal Cord Injuries
Transverse Myelitis

Interventions

BEHAVIORAL

No Results Yet

NCT06144242 | ACTIVE_NOT_RECRUITING | NA

90 participants

Improving Antibiotic Use for ARIs in Urgent Care Clinics

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-01-01
Completion:: 2025-06-30

Conditions

Antibacterial Agents
Ambulatory Care

Interventions

BEHAVIORAL

No Results Yet

NCT06142357 | ACTIVE_NOT_RECRUITING

199 participants

Secukinumab Drug Survival, Effectiveness and Tolerability in Pediatric Patients With Psoriasis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-12-29
Completion:: 2027-08-31

Conditions

Moderate-to-severe Plaque Psoriasis

Interventions

OTHER

No Results Yet

NCT06141785 | RECRUITING | NA

200 participants

Early Nutritional Intervention in Patients With Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-06-01
Completion:: 2026-03-31

Conditions

Nutritional Intervention
Cancer
Malnutrition

Interventions

OTHER

No Results Yet

NCT06132386 | COMPLETED

21 participants

Analysis of Cellular Kinases and Aging in PBMCs and Colorectal Tissue

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-08-07
Completion:: 2024-05-20

Conditions

HIV Infections
Aging

Interventions

OTHER

Results Available

NCT06105736 | RECRUITING | NA

105 participants

Regulating Together in Tuberous Sclerosis Complex

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-12-20
Completion:: 2026-12-20

Conditions

TSC
Behavioral Symptoms

Interventions

BEHAVIORAL

No Results Yet

NCT06098612 | RECRUITING | EARLY_PHASE1

40 participants

PET Imaging Evaluation of [11C]SY08

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-05-01
Completion:: 2026-11-30

Conditions

Parkinson's Disease
Multiple System Atrophy
Dementia With Lewy Bodies
Healthy Controls

Interventions

DRUG

No Results Yet

NCT06091787 | COMPLETED | NA

90 participants

Effect of Ursodeoxycholic Acid Supplementation on Liver Regeneration on Right Lobe Donor Hepatectomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-09-01
Completion:: 2024-11-30

Conditions

Liver Regeneration
Ursodeoxycholic Acid
Partial Liver Resection

Interventions

DRUG
OTHER

No Results Yet

NCT06075576 | COMPLETED

23 participants

Characterization of the Central and Peripheral Wavefront Aberration Profile in Pediatric Myopic Subjects

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-11-16
Completion:: 2025-08-11

Conditions

Myopia

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06074341 | ACTIVE_NOT_RECRUITING | NA

470 participants

TeleHealth Resources for IndiVidualizEd Goals (THRIVE) in Alcohol Recovery Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-09-13
Completion:: 2028-01-31

Conditions

Alcohol Use Disorder
Alcohol Drinking
Alcohol-Related Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06073041 | COMPLETED | NA

20 participants

Implementing and Evaluating the Integration of Physical Activity Into a Major Health System and Connecting Patients to Physical Activity Programs.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-08-03
Completion:: 2023-09-05

Conditions

Chronic Disease
Exercise
Physical Activity

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT06022081 | ACTIVE_NOT_RECRUITING | NA

60 participants

Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-09-27
Completion:: 2024-07-23

Conditions

Pneumothorax

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06022029 | RECRUITING | PHASE1

168 participants

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-10-13
Completion:: 2026-04-30

Conditions

Triple Negative Breast Cancer
Diffuse Large B Cell Lymphoma
Follicular Lymphoma
Lymphoma, Non-Hodgkin
Mantle Cell Lymphoma
Bladder Cancer
Uveal Melanoma, Recurrent
Cervix Cancer
Carcinoma in Situ
Head and Neck Squamous Cell Carcinoma
Skin Cancer
Metastatic Cancer
Tumor, Solid
Tumor Recurrence

Interventions

DRUG

No Results Yet

NCT06009276 | RECRUITING

70 participants

Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-08-30
Completion:: 2026-12-31

Conditions

Heart Failure, Systolic
Heart Failure, Diastolic
Peripheral Arterial Disease
Overweight and Obesity

No Results Yet

NCT05977322 | TERMINATED | PHASE1

24 participants

A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-10-06
Completion:: 2024-12-13

Conditions

Pancreatic Ductal Adenocarcinoma
Gastroesophageal Adenocarcinoma
Glioblastoma Multiforme

Interventions

DRUG

No Results Yet

NCT05961956 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

5 participants

Study With NVDX3 for Treatment of Low Grade Degenerative Lumbar Spondylolisthesis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-10-12
Completion:: 2026-04-18

Conditions

Degenerative Lumbar Spondylolisthesis

Interventions

DRUG

No Results Yet

NCT05938153 | COMPLETED

41 participants

Evaluation of Metabolic Syndrome, Frailty, Locomotive Syndrome, Balance and Physical Fitness in Elderly Individuals

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-06-01
Completion:: 2024-11-01

Conditions

Geriatrics
Fragility
Locomotor
Physical Fitness
Balance

Interventions

OTHER

No Results Yet

NCT05937373 | TERMINATED | NA

22 participants

Perioperative Continuous Glucose Monitoring

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-08-04
Completion:: 2024-05-21

Conditions

Diabetes Mellitus

Interventions

DEVICE
OTHER

Results Available

NCT05934773 | TERMINATED | NA

5 participants

Post-Brain Injury Walking and Balance Recovery Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2022-08-18
Completion:: 2025-04-04

Conditions

Acquired Brain Injury
Stroke
Traumatic Brain Injury

Interventions

DEVICE

No Results Yet

NCT05934136 | COMPLETED | NA

60 participants

Brain Health Program for Older Adults With Subjective Cognitive Decline

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2024-01-16
Completion:: 2025-11-07

Conditions

Memory Loss (Excluding Dementia)
Healthy Lifestyle
Risk Reduction Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT05926297 | COMPLETED | NA

92 participants

Treatment of Peri-implant Mucositis by Sodium Hypochlorite Gel and Cross-linked Hyaluronic Acid Gel

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-24
Start Date:: 2023-06-06
Completion:: 2025-07-01

Conditions

Peri-implant Mucositis
Mucositis Oral

Interventions

PROCEDURE

No Results Yet