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Treatment of Peri-implant Mucositis by Sodium Hypochlorite Gel and Cross-linked Hyaluronic Acid Gel

NCT05926297 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 92

Last updated 2025-12-24

No results posted yet for this study

Summary

The aim of the study is to evaluate the potential of the combination of a sodium hypochlorite-based gel and a hyaluronic acid-based gel as an adjuvant to Non-Surgical Mechanical Debridement (NSMD) in the treatment of mucositis, after 6 months of follow-up. After a meticulous selection, patients will be randomly assigned to Test (Sodium Hypochlorite-based gel + NSMD + Hyaluronic Acid-based gel ) or Control (NSMD) group. All clinical parameters will be recorded and the final evaluation will be performed.

Conditions

  • Peri-implant Mucositis
  • Mucositis Oral

Interventions

PROCEDURE

Application NaOCl gel + HA gel

First step: application of NaOCl gel Second step: NSMD Third step: application of HA gel

PROCEDURE

Non-surgical mechanical debridement

Only mechanical debridement with curettes ans scaler tips

Sponsors & Collaborators

  • Semmelweis University

    collaborator OTHER

  • Federico II University

    lead OTHER

Principal Investigators

  • Luca Ramaglia · Federico II University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-06-06
Primary Completion
2025-07-01
Completion
2025-07-01

Countries

  • Hungary
  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05926297 on ClinicalTrials.gov