Clinical Trials Updated in 2025

NCT07279909 | ACTIVE_NOT_RECRUITING | PHASE3

500 participants

Phase-III Clinical Studies on Poly Herbal Anti-Diabetic Formulation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-03-09
Completion:: 2025-08-01

Conditions

Diabetes Type 2
Diabetes Mellitus, Experimental
HbA1c
Urinary Glucose
Ability of Experimental Drug to Lower HbA1c Compare to Metformin

Interventions

DRUG

No Results Yet

NCT07279896 | COMPLETED

88 participants

Determination of RNA/DNA Damage Associated With Oxidative Stress in Periodontitis Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-05-05
Completion:: 2025-08-04

Conditions

Periodontitis (Stage 3)
Smoking

No Results Yet

NCT07279883 | RECRUITING

150 participants

Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block in Children Undergoing Cleft Palate Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2017-01-01
Completion:: 2018-12-31

Conditions

Cleft Palate Children

No Results Yet

NCT07279857 | NOT_YET_RECRUITING | NA

110 participants

The Impact of a Mobile Application-based Support and Counseling Program on Women's Knowledge, Attitudes and Self-efficacy in the Preconceptional Period

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-01-01
Completion:: 2026-09-01

Conditions

Preconception Period

Interventions

BEHAVIORAL

No Results Yet

NCT07279844 | NOT_YET_RECRUITING

6 participants

An Open-label, Observational, Long-term Follow-up Study Evaluating the Safety and Efficacy of RGL-193 Putamen Injection in Patients With Primary Parkinson's Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-12-15
Completion:: 2029-12-14

Conditions

Parkinson's Disease

Interventions

OTHER

No Results Yet

NCT07279818 | NOT_YET_RECRUITING | NA

132 participants

Improving Chemotherapy Induced Peripheral Neuropathy in Children With Leukemia: A Study of Transcutaneous Acupoints Electrical Stimulation and Auricular Acupressure Interventions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-12-08
Completion:: 2026-09-30

Conditions

Chemotherapy Induced Peripheral Neuropathy (CIPN)

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07279805 | COMPLETED

40 participants

Peripheral Perfusion Index as a Predictor of Post-spinal Hypotension in Patients Undergoing Lower Limb Surgeries

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-09-09
Completion:: 2025-03-09

Conditions

Post Spinal Anaesthesia Hypotension

No Results Yet

NCT07279779 | COMPLETED | NA

54 participants

HypnoDiaCare Trial: A Randomized Controlled Study of Hypnosis-Integrated Diabetes Self-Management Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-12-23
Completion:: 2025-07-31

Conditions

Type 2 Diabetes Mellitus (T2DM)

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT07279740 | RECRUITING | PHASE2

12 participants

Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-01-31
Completion:: 2027-10-01

Conditions

Alzheimer s Disease
Alzheimer Dementia (AD)
Alzheimer Dementia
Alzheimer Disease
Apathy
Apathy in Dementia

Interventions

DEVICE
DRUG

No Results Yet

NCT07279727 | NOT_YET_RECRUITING | PHASE1

66 participants

Ultrasound-Guided Infraclvicular Block Using Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Upper Limb Orthopedic Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-01-01
Completion:: 2026-12-31

Conditions

Regional Anaesthesia

Interventions

DRUG

No Results Yet

NCT07279675 | NOT_YET_RECRUITING

67 participants

Clinical Predictors of Severity in Pediatric Community-Acquired Pneumonia at Assiut University Children's Hospital

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-12-01
Completion:: 2026-12-01

Conditions

Community-Acquired Pneumonia
Pediatric Pneumonia
Lower Respiratory Tract Infection

Interventions

OTHER

No Results Yet

NCT07279662 | COMPLETED | NA

40 participants

Comparison of Skeletal Anchorage Versus Conventional Tooth-Borne Face Mask Therapy Following the Alt-RAMEC Protocol

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2023-01-05
Completion:: 2024-09-05

Conditions

Class III Malocclusion
Skeletal Malocclusion
Maxillary Deficiency

Interventions

DEVICE

No Results Yet

NCT07279623 | RECRUITING | NA

110 participants

Intra-Nasal Mechanical Stimulation (INMEST) as a Potential Preventative Treatment for Migraine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-10-21
Completion:: 2026-09-30

Conditions

Migraine

Interventions

DEVICE

No Results Yet

NCT07279610 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

44 participants

N-Acetylcysteine as Therapy for Transplantation- Associated Thrombotic Microangiopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-05-01
Completion:: 2026-12-31

Conditions

Thrombotic Microangiopathy

Interventions

DRUG

No Results Yet

NCT07279584 | NOT_YET_RECRUITING | PHASE2

31 participants

Golidocitinib Combined With GemOx in RR PTCL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-12-20
Completion:: 2026-12-31

Conditions

Peripheral T-cell Lymphomas (PTCL)

Interventions

DRUG

No Results Yet

NCT07279545 | RECRUITING | NA

80 participants

The Effect of Placental Cord Drainage on the Third Stage of Labor and the Amount of Postpartum Bleeding

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-11-17
Completion:: 2026-06-20

Conditions

Postpartum Hemorrhage

Interventions

PROCEDURE

No Results Yet

NCT07279532 | NOT_YET_RECRUITING | PHASE2

35 participants

Clinical Study of Adjuvant Surufatinib Therapy for Postoperative High-risk Neuroendocrine Tumors Based on the Ninth Edition of the AJCC Staging System

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-01-01
Completion:: 2029-12-31

Conditions

Neuroendocrine Neoplasms (Tumours)

Interventions

DRUG

No Results Yet

NCT07279506 | NOT_YET_RECRUITING | NA

180 participants

Clinical Investigation of IXIUM TWIN Viscoelastic Ophthalmic Device For Cataract Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-01-31
Completion:: 2026-09-30

Conditions

Cataract Surgery

Interventions

DEVICE

No Results Yet

NCT07279493 | RECRUITING | PHASE2

300 participants

Efficacy and Safety of the KPCXM18 Injection in Patients With Acute Ischemic Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-11-22
Completion:: 2026-10-18

Conditions

Acute Ischemic Stroke

Interventions

DRUG

No Results Yet

NCT07279480 | RECRUITING | NA

1200 participants

Communication and Health Investments for Elderly Women

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-11-10
Completion:: 2026-08-01

Conditions

Take-up of Preventative Care
Communication About Health Information

Interventions

BEHAVIORAL

No Results Yet

NCT07279467 | NOT_YET_RECRUITING

500 participants

Study of Oral Food Challenge Biomarkers (SAFER)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-04-30
Completion:: 2027-10-01

Conditions

Allergy

Interventions

DRUG

No Results Yet

NCT07279441 | RECRUITING | NA

460 participants

Cochlear Implants and Listening Effort: the Interaction of Cognitive and Sensory Constraints

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-01-02
Completion:: 2030-01-02

Conditions

Cochlear Implant Users

Interventions

BEHAVIORAL

No Results Yet

NCT07279415 | NOT_YET_RECRUITING | NA

300 participants

Activate Tennessee: A CHW-Supported Program for Patient Activation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-12-20
Completion:: 2027-09-30

Conditions

Diabetes
Hypertension
Cardio Vascular Disease
Infectious Diseases Morbidity
Chronic Kidney Disease
Hypercholesterolemia

Interventions

BEHAVIORAL

No Results Yet

NCT07279389 | COMPLETED | NA

60 participants

Comparative Study Between One-Shot Dilatation Versus Serial Dilatation Techniques for Access in Percutaneous Nephrolithotomy in Adult Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2022-02-27
Completion:: 2022-08-27

Conditions

Percutaneous Nephrolithotomy (PCNL)
Renal Stone Disease

Interventions

PROCEDURE

No Results Yet

NCT07279337 | COMPLETED | NA

60 participants

Effectiveness of Nutrition Counseling on Gestational Weight Gain Among Overweight and Obese Pregnant Women in Lebanon

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2021-02-01
Completion:: 2022-03-20

Conditions

Overweight and Obesity During Pregnancy

Interventions

BEHAVIORAL

No Results Yet

NCT07279324 | NOT_YET_RECRUITING | NA

45 participants

Safety and Efficacy of Kelulut Honey Eyedrops in Dry Eye Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-04-01
Completion:: 2026-07-30

Conditions

Dry Eye Disease (DED)
Dry Eye Syndrome (DES)
Dry Eye Symptoms

Interventions

DRUG

No Results Yet

NCT07279246 | COMPLETED | NA

92 participants

The Effects of Exercise and Music Combination on Drug Cravings, Depression and Self-Efficacy Among Drug Addicts

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2024-03-15
Completion:: 2024-09-15

Conditions

Drug Craving Levels Among Individuals With Substance Addiction
Depression Levels Among Individuals With Substance Addiction
Self-efficacy Among Individuals With Substance Addiction

Interventions

BEHAVIORAL

No Results Yet

NCT07279220 | NOT_YET_RECRUITING | NA

238 participants

Safety and Effectiveness of the Vascular Closure Device for Femoral Artery Hemostasis in Patients of Femoral Artery Puncture

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-12-29
Completion:: 2026-03-02

Conditions

Femoral Artery Puncture
Vascular Closure Device
Hemostasis

Interventions

DEVICE

No Results Yet

NCT07279207 | NOT_YET_RECRUITING

500 participants

PACE-AF: Prospective Analysis of Cardiac Electrostimulation and Atrial Fibrillation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-12-31
Completion:: 2027-12-31

Conditions

Atrial Fibrillation
Sick Sinus Syndrome
Atrioventricular Block

No Results Yet

NCT07279194 | RECRUITING | PHASE3

825 participants

Efficacy and Safety of HDM1005 in Chinese Obesity or Overweight Patients Without Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-10-14
Completion:: 2026-09-20

Conditions

Obesity & Overweight

Interventions

DRUG

No Results Yet

NCT07279168 | NOT_YET_RECRUITING | NA

186 participants

Investigation of the Effectiveness of Virtual Reality (VR) Hypnosis in Improving Poor Sleep Among Chinese Childhood Cancer Survivors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-01-01
Completion:: 2028-09-30

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT07279155 | COMPLETED | PHASE1

36 participants

A Study on the Bioequivalence of Bupivacaine Liposome Injection in Humans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-06-09
Completion:: 2025-07-21

Conditions

Postoperative Local Analgesia

Interventions

DRUG

No Results Yet

NCT07279142 | NOT_YET_RECRUITING | NA

48 participants

Efficacy and Safety of 7 Millimeters Vaginal Radiofrequency in Overactive Bladder

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-12-16
Completion:: 2026-11-13

Conditions

Overactive Bladder (OAB)
Incontinence, Urge

Interventions

DEVICE

No Results Yet

NCT07279129 | NOT_YET_RECRUITING | PHASE1

120 participants

Decision Support Tool to Integrate PrEP Into Emergency Departments

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2027-01-15
Completion:: 2028-04-15

Conditions

HIV

Interventions

BEHAVIORAL

No Results Yet

NCT07279064 | NOT_YET_RECRUITING

70 participants

Central Venous Pressure Versus Inferior Vena Cava Distensibility Index in Assessing Fluid Responsiveness in Septic Shocked Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-01-31
Completion:: 2027-10-31

Conditions

Central Venous Pressure and Inferior Vena Cava Distensibility Index in Assessing Fluid Responsiveness in Septic Shocked Patients

Interventions

DEVICE

No Results Yet

NCT07279051 | NOT_YET_RECRUITING | NA

224 participants

Modified Mini-Open TLIF vs Traditional Open TLIF

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-12-06
Completion:: 2028-05-01

Conditions

Spinal Stenosis Lumbar

Interventions

PROCEDURE

No Results Yet

NCT07279038 | NOT_YET_RECRUITING

650 participants

Pivotal U.S. Clinical Validation of AI-COA® for Depression and Anxiety

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2027-03-01
Completion:: 2029-08-28

Conditions

Depression Disorders
Anxiety Disorders

No Results Yet

NCT07279025 | NOT_YET_RECRUITING

150 participants

Validate the Temporal Stability and Responsiveness of AI-COA® for Depression and Anxiety

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2026-03-01
Completion:: 2027-02-28

Conditions

Depression Disorders
Anxiety Disorders

No Results Yet

NCT07278986 | RECRUITING | EARLY_PHASE1

10 participants

CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-10-18
Completion:: 2027-10-31

Conditions

Endometrial Cancer
Near Infrared Fluorescence Imaging
CYTALUX (Pafolacianine) Injection
Planned Diagnostic Laparoscopies

Interventions

DRUG
DEVICE

No Results Yet

NCT07278960 | RECRUITING

300 participants

Enhancing Management Algorithms for Children Conceived Via Assisted Reproductive Technologies

Study Type:: OBSERVATIONAL
Last Updated:: 2025-12-12
Start Date:: 2025-10-01
Completion:: 2026-06-30

Conditions

Children
ART
Anthropometric Characteristics
Somatic Health Status
Neurological Condition
Urogenital Pathology

Interventions

DIAGNOSTIC_TEST

No Results Yet