Clinical Trials Updated in 2025

NCT07251920 | COMPLETED | PHASE3

30 participants

Isometric Resistance Training and Dose-dependent Effects in Pre- and Hypertensive Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2024-02-19
Completion:: 2024-05-20

Conditions

Hypertension
Blood Pressure, High

Interventions

OTHER

No Results Yet

NCT07251868 | RECRUITING

100 participants

Evaluation of Trop-2 ADC in Breast Cancer Patients With Brain Metastases: A Real-World Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2024-08-01
Completion:: 2026-12-31

Conditions

Breast Cancer
Brain Metastases From Breast Cancer
Trop2

Interventions

DRUG

No Results Yet

NCT07251855 | COMPLETED | NA

56 participants

Development and Effectiveness of the Occupational Activities Module on the Quality of Life of Older Persons

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2024-05-20
Completion:: 2024-08-28

Conditions

Ageing and Geriatric Health

Interventions

BEHAVIORAL

No Results Yet

NCT07251829 | NOT_YET_RECRUITING | PHASE2

35 participants

Neoadjuvant Embolization and Cytoreduction in Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2026-02-28
Completion:: 2027-07-31

Conditions

Prostate Adenocarcinoma

Interventions

PROCEDURE

No Results Yet

NCT07251777 | COMPLETED | NA

254 participants

Prone vs Supine Position in Potential Organ Donors: Multicenter Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2023-06-01
Completion:: 2024-12-31

Conditions

Prone Position
Donors
Lung Procurement
Tissue Donors
Lung Transplantation

Interventions

PROCEDURE

No Results Yet

NCT07251764 | COMPLETED

140 participants

The Blood-Interstitial Glucose Gap

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2023-07-13
Completion:: 2024-03-13

Conditions

Critical Illness
Metabolism Disorders

No Results Yet

NCT07251738 | NOT_YET_RECRUITING

66 participants

Understanding the Lived Experience and Bereavement of Caregivers of People With Alzheimer's Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-12-01
Completion:: 2026-05-31

Conditions

Alzheimer Disease (AD)
Occupational Therapy
Family Caregivers

Interventions

OTHER

No Results Yet

NCT07251725 | RECRUITING

126 participants

GEN-FPF: Genetic Exploration of Familial Pulmonary Fibrosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-17
Completion:: 2028-09-30

Conditions

Familial Pulmonary Fibrosis

No Results Yet

NCT07251699 | ENROLLING_BY_INVITATION | NA

28 participants

EFFECT OF EARLY WEIGHT BEARING AND ACTIVE KNEE EXERCISES IN TREATMENT OF TIBIAL PLATEAU FRACTURES

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2024-11-01
Completion:: 2026-11-01

Conditions

Tibial Plateau Fractures

Interventions

OTHER

No Results Yet

NCT07251660 | NOT_YET_RECRUITING | NA

32 participants

Comparison of Early Postoperative Outcomes Between Minimally Invasive Valve Surgery Via Right Thoracotomy and Conventional Valve Surgery Via Sternotomy.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-12-15
Completion:: 2026-07-15

Conditions

Heart Valve Diseases or Prosthesis
Aortic Valve Stenosis
Aortic Valve Insufficiency
Valvular Heart Disease Stenosis and Regurgitation (Diagnosis)

Interventions

PROCEDURE

No Results Yet

NCT07251634 | NOT_YET_RECRUITING | NA

125 participants

Construction of a Reference Corridor to Assess the Value of Combining Innovative Morphological and Functional Analysis Techniques in Pediatric Patient Care Based on Different Pathological Models

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-12-01
Completion:: 2028-12-01

Conditions

Healthy Volunteers

Interventions

DEVICE

No Results Yet

NCT07251621 | COMPLETED | NA

150 participants

Evaluation of the Application Effect of a Surgical Navigation System in HoLEP Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2024-04-01
Completion:: 2024-09-30

Conditions

Benign Prostate Hypertrophy(BPH)

Interventions

PROCEDURE

No Results Yet

NCT07251608 | RECRUITING | PHASE1

40 participants

Randomized, Open-label, Safety Study of Subcutaneous and Intramuscular Injections of Niagen® Plus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-10-01
Completion:: 2026-02-15

Conditions

Healthy Volunteer
Fatigue

Interventions

DRUG

No Results Yet

NCT07251569 | COMPLETED | NA

97 participants

The Effect of Mobile App Counseling on Postpartum Contraception Choices and Use

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-01-22
Completion:: 2025-08-27

Conditions

Contraception Use

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT07251543 | ENROLLING_BY_INVITATION | NA

108 participants

Effects of a Salivary Gland Massage Program on Salivary Flow , Xerostomia, Chewing, and Swallowing, and Oral Health Among Community- Dwelling Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-09-02
Completion:: 2025-12-15

Conditions

Oral Health Care

Interventions

BEHAVIORAL

No Results Yet

NCT07251478 | NOT_YET_RECRUITING | NA

74 participants

Transparent Communication to Improve Mental Wellbeing and Attitude Towards Reintegration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-12-10
Completion:: 2026-09-30

Conditions

Depression
Anxiety
Trauma
Stress
Trauma, Psychological

Interventions

BEHAVIORAL

No Results Yet

NCT07251439 | NOT_YET_RECRUITING

144 participants

Impact of Perioperative Body Temperature on Postoperative Complications and Pain in Video-assisted Thoracoscopic Surgery Patients Utilizing Continuous Temperature Monitoring

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2026-01-01
Completion:: 2027-12-31

Conditions

Lung Cancer (Diagnosis)
Pain Management
Postoperative Complications
Body Temperature Measurement

Interventions

DEVICE

No Results Yet

NCT07251426 | NOT_YET_RECRUITING | NA

494 participants

Cold atmOspheric plaSMa Therapy Versus standArd Wound Care in Diabetic Foot and Venous Leg ulcerS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-30
Completion:: 2028-05-30

Conditions

Diabetic Foot Ulcer
Venous Leg Ulcer

Interventions

DEVICE

No Results Yet

NCT07251374 | NOT_YET_RECRUITING

2000 participants

Osteomyelitis Multi-center Prospective Cohort Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-12-10
Completion:: 2027-12-31

Conditions

Osteomyelitis of Lower Extremities

No Results Yet

NCT07251361 | ENROLLING_BY_INVITATION | NA

150 participants

Effects of a Multicomponent Training Program on Cardiac Function, Skeletal Muscle Metabolism, Functional Capacity, and Quality of Life in Patients With HFpEF: SENSORFIT-4HEART Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-01-20
Completion:: 2025-02-01

Conditions

Heart Failure With Preserved Ejection Fraction (HFPEF)

Interventions

BEHAVIORAL

No Results Yet

NCT07251322 | COMPLETED

14 participants

Relationship Between Frailty and Gut Microbiota in Older Adults: An Educational Program for Healthy Aging

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-08-25
Completion:: 2025-09-22

Conditions

Frailty
Microbiota

Interventions

OTHER

No Results Yet

NCT07251309 | RECRUITING | PHASE3

420 participants

A Two-Part, Phase 3 Study Evaluating the Efficacy and Safety of WS016 for the Treatment of Hyperkalemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2024-12-23
Completion:: 2026-11-30

Conditions

Hyperkalemia

Interventions

DRUG

No Results Yet

NCT07251283 | RECRUITING | NA

40 participants

Food Insecurity and Eating Behavior Among Adults Receiving Buprenorphine or Methadone Maintenance Treatment: Pilot Study 2

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-07
Completion:: 2027-07-31

Conditions

Food Security

Interventions

OTHER

No Results Yet

NCT07251205 | RECRUITING | NA

50 participants

Evaluating a Culinary Curriculum Program for Residents of Medication Assisted Therapy (MAT) Recovery Houses

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-08-11
Completion:: 2025-12-01

Conditions

Cooking Skills

Interventions

BEHAVIORAL

No Results Yet

NCT07251140 | RECRUITING | NA

50 participants

Dysphagia Study Using Novel Microphone Device

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-10-12
Completion:: 2026-09-30

Conditions

Dysphagia
Stroke

Interventions

DEVICE

No Results Yet

NCT07251127 | COMPLETED | PHASE1

18 participants

Study of Metronidazole Delayed-Release Capsules in Comparison With Immediate-Release Tablets (Flagyl) for Safety and Pharmacokinetics

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-05-27
Completion:: 2025-06-06

Conditions

Clostridium Difficile Infection (CDI)

Interventions

DRUG

No Results Yet

NCT07251114 | RECRUITING | NA

200 participants

AI-assisted Endoscopic Ultrasound Grading of Early Esophageal Cancer Invasion Depth: A Multicenter, Prospective, Randomized Cohort Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-20
Completion:: 2027-10-31

Conditions

Esophageal Cancer Stage
Early Esophageal Cancer

Interventions

DEVICE

No Results Yet

NCT07251075 | NOT_YET_RECRUITING

200 participants

Clinical Performance of a Point-of-Care Creatinine Testing System in Individuals With Kidney Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-30
Completion:: 2025-12-30

Conditions

Chronic Kidney Diseases
Kidney Injury, Acute

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07251062 | NOT_YET_RECRUITING | PHASE2/PHASE3

737 participants

A Study of SYS6010, Enlonstobart, and Chemotherapy for First-Line Treatment of Esophageal Squamous Cell Carcinoma.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-12-30
Completion:: 2029-12-30

Conditions

Esophageal Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT07251049 | RECRUITING

100 participants

Acute Infectious Encephalitis and Myelitis in Guadeloupe by New Generation Sequencing

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2023-11-16
Completion:: 2028-11-16

Conditions

Acute Encephalitis
Acute Myelitis

No Results Yet

NCT07251036 | RECRUITING | NA

3000 participants

Serum Chordecone Concentration in Guadeloupean Population: Impact of a Multidisciplinary Support Program on the Reduction of the Contamination Level.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2022-06-26
Completion:: 2028-06-30

Conditions

Chlordecone Level

Interventions

OTHER

No Results Yet

NCT07251010 | NOT_YET_RECRUITING | NA

60 participants

Phrenoesophageal Ligament Reconstruction With Mesh

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-12-20
Completion:: 2027-11-30

Conditions

Hiatus Hernia
Gastreoesophageal Reflux Disease

Interventions

PROCEDURE

No Results Yet

NCT07250971 | COMPLETED | NA

40 participants

Virtual Reality-Based Psychotherapeutic and Psychoeducational Intervention for Anxiety and Depression in Children, Adolescents, and Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-07-09
Completion:: 2025-08-15

Conditions

Anxiety Disorders
Depressive Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT07250932 | NOT_YET_RECRUITING | NA

80 participants

Exploring the Effectiveness of Somatosensory Cognitive Game Intervention on Cognitive and Physical Functions

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-30
Completion:: 2026-12-31

Conditions

Cognitive Function

Interventions

OTHER

No Results Yet

NCT07250880 | NOT_YET_RECRUITING

80 participants

Evaluation of Serum Ceramides C16, C24, and Sphingosine-1-Phosphate (S1P) in Patients With Acne Vulgaris

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-11-30
Completion:: 2026-06-30

Conditions

Acne Vulgaris

Interventions

OTHER

No Results Yet

NCT07250867 | NOT_YET_RECRUITING | PHASE2

105 participants

Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2026-01-31
Completion:: 2027-01-31

Conditions

Orofacial Pain

Interventions

DRUG

No Results Yet

NCT07250789 | RECRUITING | NA

420 participants

Cognitive Screening and Multidomain Intervention Targeting Cognitive Decline in Type 2 Diabetes (The Brain Care Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2024-06-01
Completion:: 2029-06-30

Conditions

Diabetes
Diabetes Mellitus Type 2
Type 2 Diabetes
Type 2 Diabetes Mellitus (T2DM)
Cognitive Impairment
Cognitive Decline

Interventions

OTHER

No Results Yet

NCT07250776 | COMPLETED | NA

51 participants

Effects of Body Awareness Therapy on Functional Capacity, With Peripheral Artery Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-06-30
Completion:: 2025-11-17

Conditions

Peripheral Arterial Disease

Interventions

PROCEDURE

No Results Yet

NCT07250763 | ACTIVE_NOT_RECRUITING | PHASE4

145 participants

Therapeutic Initial Heparin Dosing for Patients With Clots or Certain Heart Conditions Admitted to the Hospital

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2023-09-20
Completion:: 2027-02-28

Conditions

Pulmonary Embolism
Deep Vein Thrombosis
Atrial Fibrillation
Acute Cardiac Syndrome
Mechanical Heart Valve Recipients

Interventions

DRUG

No Results Yet

NCT07250698 | NOT_YET_RECRUITING | NA

40 participants

Glucose Control in Type 2 Diabetes in Pregnancy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-26
Start Date:: 2025-12-31
Completion:: 2026-12-31

Conditions

Pregestational Diabetes
Type 2 Diabetes

Interventions

BEHAVIORAL

No Results Yet