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Isometric Resistance Training and Dose-dependent Effects in Pre- and Hypertensive Adults

NCT07251920 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-11-26

No results posted yet for this study

Summary

High blood pressure is prevalent in a third of the global population and is a key risk factor for cardiovascular disease, the leading cause of death. one lifestyle change that is recommended to reduce blood pressure is to exercise, typically by performing aerobic exercise, but this is often not well adhered to, given the physical and time demands associated with it. Isometric resistance training has been evidenced as an efficacious method to reduce blood pressure, even when performing four two-minute contractions per day, three days per week at 30% of maximum effort. At present, the dose-response effects have not been examined, which are required to identify the minimal effective dose, which could further reduce the temporal demands of this modality to potentially enhance adhernece even more in time-anxious individuals. Therefore, this study aimed to compare the efficacy of once- twice-, and thrice-weekly isometric resistance training programmes to lower blood pressure,

Conditions

Interventions

OTHER

Isometric resistance training

isometric resistance training was performed on the chest, arms, and leg muscle groups using a band. Each contraction, was pulled at a perceived 30% (using a CR10 perceieved exertion rating scale) of maximum effort for 2 minutes; one repetition was performed using each muscle group. Weekly frequnecy changed between groups, ranging from once to thrice per week.

Sponsors & Collaborators

  • The University of Northampton

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-02-19
Primary Completion
2024-05-20
Completion
2024-05-21

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07251920 on ClinicalTrials.gov