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Relationship Between Frailty and Gut Microbiota in Older Adults: An Educational Program for Healthy Aging

NCT07251322 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 14

Last updated 2025-11-26

No results posted yet for this study

Summary

The main objective of this pre-experimental study is to describe the relationship between gut microbiota and changes in the degree of frailty in older adults who participated in an educational program. More specifically, the study aims to: determine the gut microbiota profile of community-dwelling older adults, both robust and frail; analyze the effect of a 12-month educational program on gut microbiota; examine the association of gut microbiota with physical function, functional dependency, and physical activity in frail or pre-frail older adults who received the program; investigate its relationship with the risk of malnutrition; relate the gut microbiota profile to quality of life, depressive symptoms, and social support; and, finally, associate gut microbiota with cognitive frailty and sleep quality in this group of older adults who participated in the health promotion educational intervention.

Conditions

Interventions

OTHER

Fecal sample collection

Fecal samples were collected by the participants themselves at home, who were instructed to collect a small stool sample either on the morning of the delivery day or the evening of the previous day. For home sample collection, participants were provided with a fecal sample collection kit that included a hermetically sealed sterile container, a fecal sample stabilizer (reference SC0012, Canvax brand), gloves, and a small spoon. Participants were instructed to collect a small fecal sample using the spoon and place it into the container, mixing it by shaking to combine it with the stabilizer.

Sponsors & Collaborators

  • Fundación ASISA

    collaborator UNKNOWN

  • University of Cadiz

    lead OTHER

Principal Investigators

  • Cristina Casals Vázquez · University of Cádiz

  • Juan Corral Pérez · University of Cádiz

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-25
Primary Completion
2025-09-22
Completion
2025-09-24

Countries

  • Spain

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07251322 on ClinicalTrials.gov