Clinical Trials Updated in 2025

NCT06272461 | RECRUITING | NA

50 participants

Comparison of Intravenous Lidocaine vs Ketamine in Colorectal Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-10-01
Completion:: 2026-02-10

Conditions

Colorectal (Colon or Rectal) Cancer
Inflammation

Interventions

DRUG

No Results Yet

NCT06262607 | COMPLETED | PHASE2

59 participants

A Study of CLE-400 (Topical Gel) for the Treatment of Chronic Pruritus in Adult Subjects With Notalgia Paresthetica

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-01-29
Completion:: 2024-11-06

Conditions

Chronic Pruritus in Adult Subjects With Notalgia Paresthetica (NP)

Interventions

DRUG

Results Available

NCT06222645 | RECRUITING | NA

200 participants

PPG vs. ICG in Gastrointestinal Resections

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-11-01
Completion:: 2026-04-30

Conditions

Anastomosis
Perfusion
Postoperative Complications
Gastrointestinal Neoplasms
Gastric Cancer (GC)
Colorectal Cancer

Interventions

DRUG
DEVICE

No Results Yet

NCT06222281 | COMPLETED

34 participants

Evaluation of Shoulder Strength and Deltoid Stiffness After Reverse Shoulder Arthroplasty (RSA)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2025-05-20
Completion:: 2025-06-15

Conditions

Sonoelastography
Isokinetic Test

No Results Yet

NCT06218433 | RECRUITING | NA

200 participants

Urothelial Cancer Screening in Individuals With Lynch Syndrome Using a Urine Tumor DNA Panel (LS-URO Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-04-10
Completion:: 2026-12-30

Conditions

Urothelial Carcinoma
Lynch Syndrome

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06212141 | ACTIVE_NOT_RECRUITING | NA

54 participants

Comparison of Bulk-Fill Composite Resins in Class II Restorations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-12-12
Completion:: 2024-06-15

Conditions

Class II Dental Caries

Interventions

DEVICE

No Results Yet

NCT06201793 | COMPLETED | PHASE2

46 participants

Minocyclin in Ulcerative Colitis as Added on Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-01-22
Completion:: 2025-01-20

Conditions

Inflammatory Bowel Diseases

Interventions

DRUG

No Results Yet

NCT06192667 | ACTIVE_NOT_RECRUITING | NA

30 participants

Clinical Performance of Injectable Composite Resins in Class I Cavities

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-06-12
Completion:: 2024-02-15

Conditions

Caries,Dental

Interventions

DEVICE

No Results Yet

NCT06177522 | NOT_YET_RECRUITING | PHASE2

30 participants

Adebrelimab Combined With Chemotherapy for Neoadjuvant Therapy in Resectable Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2025-11-30
Completion:: 2027-12-30

Conditions

Pancreatic Cancer
Neoadjuvant Therapy

Interventions

DRUG

No Results Yet

NCT06176170 | ACTIVE_NOT_RECRUITING | NA

65 participants

VividWhite Glaucoma Implant (VW-51) Pivotal Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-12-12
Completion:: 2026-10-31

Conditions

Glaucoma

Interventions

DEVICE

No Results Yet

NCT06165081 | RECRUITING

6000 participants

The Association Between Post-resuscitation Time Series Management in the Emergency Department and Short-term Outcomes for Out-of-hospital Cardiac Arrest Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-01-01
Completion:: 2026-12-31

Conditions

Resuscitation
Emergency Department
Outcome

No Results Yet

NCT06146335 | COMPLETED | NA

11 participants

Analysis of Biologic Signatures in Crohn's Patients Undergoing Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-01-03
Completion:: 2025-05-31

Conditions

Crohn Disease

Interventions

PROCEDURE

No Results Yet

NCT06143917 | COMPLETED | NA

306 participants

Efficacy of Parent-child Sleep Intervention

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-02-20
Completion:: 2025-05-24

Conditions

Sleep Quality
Psychological Health
Infant Health

Interventions

BEHAVIORAL

No Results Yet

NCT06141564 | ACTIVE_NOT_RECRUITING

360 participants

Detect and Expunge Concealed Tumors of the Liver

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-10-16
Completion:: 2026-10-31

Conditions

Liver Cancer

No Results Yet

NCT06139809 | COMPLETED | NA

50 participants

Noninvasive Positive Pressure Ventilation During Neonatal Nasal Intubation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-03-31
Completion:: 2025-10-05

Conditions

Infant, Newborn, Diseases
Intubation Complication

Interventions

PROCEDURE

No Results Yet

NCT06139692 | RECRUITING | PHASE4

810 participants

Comparison of Perioperative Conscious Sedation During Endovascular Thrombectomy in Acute Ischemic Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-11-21
Completion:: 2026-06-13

Conditions

Acute Ischemic Stroke

Interventions

DRUG

No Results Yet

NCT06127784 | RECRUITING | NA

176 participants

Survivorship After HNC: A Randomized Controlled Trial Evaluating Patient Care and Adherence to Follow-up

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2025-05-01
Completion:: 2026-01-01

Conditions

Head and Neck Cancer
Survivorship

Interventions

OTHER

No Results Yet

NCT06120439 | COMPLETED | NA

96 participants

Comparing the QoR of PECS Block and GA in Breast-conserving Surgery With Sentinel Lymph Node Biopsy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-12-01
Completion:: 2024-05-11

Conditions

Breast Cancer
Pectoral Nerves Block
Breast-Conserving Surgery
Sentinel Lymph Node Biopsy

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06119698 | RECRUITING | NA

200 participants

Improving Health for Older Adults With Pain Through Engagement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-10-01
Completion:: 2027-04-01

Conditions

Chronic Pain
Musculoskeletal Pain

Interventions

BEHAVIORAL

No Results Yet

NCT06115369 | COMPLETED | NA

150 participants

Food Supplementation Delivered Conditionally vs Not Among Patients With Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-04-15
Completion:: 2025-10-15

Conditions

Heart Failure

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06086340 | COMPLETED

779 participants

Study to Compare Overall Survival in Medicare Patients With Metastatic Breast Cancer Treated With a Medicine Called Palbociclib in Combination With Aromatase Inhibitor and Aromatase Inhibitor by Itself.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-09-29
Completion:: 2024-01-24

Conditions

Breast Cancer

Interventions

DRUG

Results Available

NCT06079047 | COMPLETED | NA

66 participants

Perineural Dexamethasone in the Adductor Canal Block

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-12-15
Completion:: 2025-10-31

Conditions

Post Operative Pain

Interventions

PROCEDURE

No Results Yet

NCT06077747 | RECRUITING | NA

4 participants

Lumbar Vein Embolization for Chronic Headaches With Nutcracker Physiology

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-09-17
Completion:: 2027-09-30

Conditions

Chronic Headache
Nutcracker Phenomenon, Renal
Nutcracker Syndrome, Renal

Interventions

PROCEDURE

No Results Yet

NCT06061952 | COMPLETED | NA

36 participants

CAE for Poorly Adherent Individuals With Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-01-16
Completion:: 2025-08-09

Conditions

Schizophrenia

Interventions

BEHAVIORAL
OTHER

Results Available

NCT06057766 | RECRUITING | NA

90 participants

Physical Activity Coaching After Surgery for Patients With Resectable Non-small Cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-01-01
Completion:: 2026-08-01

Conditions

Non Small Cell Lung Cancer
Non-small Cell Carcinoma

Interventions

OTHER

No Results Yet

NCT06048068 | COMPLETED | NA

53 participants

Removing Surrogates' Uncertainty to Reduce Fear and Anxiety After Cardiac Events

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-09-07
Completion:: 2024-10-14

Conditions

Cardiac Arrest

Interventions

BEHAVIORAL

Results Available

NCT06042855 | COMPLETED | PHASE3

3214 participants

ACTIV-6: COVID-19 Study of Repurposed Medications - Arm G (Metformin)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-09-05
Completion:: 2024-06-03

Conditions

Covid19

Interventions

OTHER
DRUG

Results Available

NCT06039020 | ACTIVE_NOT_RECRUITING

1 participants

ATGAM General Investigation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-02-21
Completion:: 2027-01-22

Conditions

Aplastic Anemia

Interventions

DRUG

No Results Yet

NCT06038032 | RECRUITING | NA

148 participants

ImpRoving hEalth behaviourS for LIfe After ENdometrial CancEr Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-03-25
Completion:: 2028-03-31

Conditions

Endometrial Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06032507 | COMPLETED | NA

100 participants

Effect of High-pressure Pulsatile Lavage Versus Manual Rinsing on Bone Cement Penetration in Total Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-03-01
Completion:: 2023-03-01

Conditions

Knee

Interventions

PROCEDURE

No Results Yet

NCT06027606 | COMPLETED | PHASE1

81 participants

Cardiovascular Consequences of Inhaled Short-acting Beta-agonist Use

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-09-01
Completion:: 2025-09-25

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT06025227 | AVAILABLE

Provide Pre-approval Single Patient Expanded Access (Compassionate Use) of Etrasimod for Patients.

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-11-18

Conditions

Colitis, Ulcerative

Interventions

DRUG

No Results Yet

NCT06000319 | ENROLLING_BY_INVITATION

200 participants

Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-01-04
Completion:: 2027-02-01

Conditions

Degenerative Disc Disease
Degenerative Spondylolisthesis
Spinal Stenosis

Interventions

BIOLOGICAL
PROCEDURE

No Results Yet

NCT05999344 | COMPLETED | NA

146 participants

Alcohol and Cannabis Concentrates Co-Administration

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-12-16
Completion:: 2024-08-01

Conditions

Alcohol Use Disorder
Cannabis Use

Interventions

OTHER

No Results Yet

NCT05992857 | RECRUITING | NA

150 participants

Pancreaticoduodenectomies With Complete Arterial Coverage by Retromesenteric Omentoplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2024-10-22
Completion:: 2027-01-31

Conditions

Pancreatectomy
Complication of Surgical Procedure

Interventions

PROCEDURE

No Results Yet

NCT05989620 | RECRUITING

1000 participants

Long-Term Development of Muscular Dystrophy Outcome Assessments

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-10-18
Completion:: 2028-10-01

Conditions

LGMD1B
LGMD1C
LGMD1D
LGMD1E
LGMD1F
LGMD1G
LGMD1H
LGMD2A
LGMD2B
LGMD2C
LGMD2D
LGMD2E
LGMD2F
LGMD2G
LGMD2I
LGMD2J
LGMD2K
LGMD2L
LGMD2M
LGMD2N
LGMD2O
LGMD2P
LGMD2Q
LGMD2S
LGMD2T
LGMD2U
LGMD2W
LGMD2X
LGMD2Y

No Results Yet

NCT05984875 | RECRUITING

74 participants

The Immune Landscape of Epithelial Ovarian Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2022-12-20
Completion:: 2026-12-31

Conditions

Epithelial Ovarian Cancer

Interventions

OTHER

No Results Yet

NCT05968352 | WITHDRAWN

0 participants

Restoration of Bladder Function in Spinal Cord Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2025-11-18
Start Date:: 2021-11-18
Completion:: 2025-10-14

Conditions

Bladder Dysfunction
Spinal Cord Injuries

Interventions

DEVICE

No Results Yet

NCT05960331 | RECRUITING | NA

72 participants

Influence of Autonomy on Motor Learning in People With Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2023-08-21
Completion:: 2025-07-31

Conditions

Parkinson Disease

Interventions

BEHAVIORAL

No Results Yet

NCT05951595 | RECRUITING | PHASE3

1680 participants

A Study to Find Out if a Combination of 3 Medicines for the Treatment of Malaria Works as Well and is as Safe and Tolerable as Combinations of 2 Medicines

Study Type:: INTERVENTIONAL
Last Updated:: 2025-11-18
Start Date:: 2025-09-11
Completion:: 2026-07-31

Conditions

Uncomplicated Plasmodium Falciparum Malaria

Interventions

DRUG

No Results Yet