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Comparison of Intravenous Lidocaine vs Ketamine in Colorectal Surgery

NCT06272461 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2025-11-18

No results posted yet for this study

Summary

Patients undergoing open colorectal surgery were randomly divided into two groups: Intravenous Lidocaine (IV-Lido) vs Intravenous Ketamine (IV-Keta).

For the IV-Lido group, patients received a loading dose of Lidocaine than a continuous infusion over twenty-four hours.

For the IV-Keta goup, patients received a loading dose of Ketamine than a continuous injection of Ketamine over twenty-four hours.

Plasma concentrations of Interleukin-6(IL-6) were measured preoperatively before anesthetic induction and at twenty-four hour post operatively.

Conditions

Interventions

DRUG

Lidocaine IV

Intravenous Lidocaine Vs intravenous Ketamine in colorectal surgery for cancer

DRUG

Ketamine Injectable Solution

Intravenous Lidocaine Vs intravenous Ketamine in colorectal surgery for cancer

Sponsors & Collaborators

  • University Tunis El Manar

    lead OTHER

Principal Investigators

  • BEN ALI MECHAAL, Professor · university manar Tunis, Tunisia

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-01
Primary Completion
2026-02-10
Completion
2026-03-30

Countries

  • Tunisia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06272461 on ClinicalTrials.gov