Clinical Trials

NCT04638660 | COMPLETED | PHASE3

144 participants

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) in Subjects With Dim Light Vision Disturbances

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2020-12-30

Completion:

2022-05-19

Conditions

• Dim Light Vision Disturbances

Interventions

• DRUG

Results Available

NCT04520451 | COMPLETED | PHASE2

27 participants

Open Label Two-Arm Study to Evaluate Rilzabrutinib in IgG4-Related Disease Participants

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2020-08-22

Completion:

2024-10-15

Conditions

• Immunoglobulin G4 Related Disease

Interventions

• DRUG

No Results Yet

NCT04520373 | ACTIVE_NOT_RECRUITING | PHASE2

40 participants

Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2020-06-25

Completion:

2026-07-31

Conditions

• Spinal Cord Injuries
• Paralysis

Interventions

• OTHER
• BIOLOGICAL

No Results Yet

NCT04517669 | COMPLETED

116 participants

Effectiveness of Treatment With Tofacitinib in Patients With Psoriatic Arthritis in Routine Clinical Practice

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-14

Start Date:

2021-05-17

Completion:

2024-07-30

Conditions

• Psoriatic Arthritis

Results Available

NCT04508049 | ACTIVE_NOT_RECRUITING | NA

24 participants

A Study to Evaluate Renal Fibrosis Using MRI Techniques

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2020-10-01

Completion:

2026-09-30

Conditions

• Hypertension
• Renovascular

Interventions

• DEVICE

No Results Yet

NCT04488133 | COMPLETED | PHASE4

46 participants

A Study to Learn About the Effect of Nusinersen (BIIB058) Given as Injections to Children With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene Abeparvovec (RESPOND)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2021-01-04

Completion:

2025-10-09

Conditions

• Muscular Atrophy, Spinal

Interventions

• DRUG

No Results Yet

NCT04481373 | COMPLETED | NA

75 participants

Targeting HIV Retention and Improved Viral Load Through Engagement ('THRIVE')

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2021-03-03

Completion:

2024-02-29

Conditions

• Human Immunodeficiency Virus
• Depression
• Anxiety

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT04476953 | ACTIVE_NOT_RECRUITING | PHASE2

80 participants

COVID-FISETIN: Pilot in SARS-CoV-2 of Fisetin to Alleviate Dysfunction and Inflammation

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2020-08-03

Completion:

2026-09-30

Conditions

• Covid19

Interventions

• DRUG

No Results Yet

NCT04441567 | RECRUITING | NA

3000 participants

Right-Size Clinic Visits Using Memora Platform for PROMIS

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2021-05-10

Completion:

2026-09-30

Conditions

• Orthopedic Disorders

Interventions

• OTHER

No Results Yet

NCT04438824 | ACTIVE_NOT_RECRUITING | PHASE2

42 participants

Palbociclib and INCMGA00012 in People With Advanced Liposarcoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2020-06-17

Completion:

2026-06-30

Conditions

• Well-differentiated/Dedifferentiated Liposarcoma

Interventions

• DRUG

No Results Yet

NCT04419181 | WITHDRAWN | PHASE2

0 participants

Feasibility of Chemotherapy De-escalation in Early-Stage HER2 Positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2025-08-11

Completion:

2026-06-01

Conditions

• HER2-positive Breast Cancer

Interventions

• DRUG

No Results Yet

NCT04379011 | COMPLETED | PHASE1/PHASE2

24 participants

Brivaracetam to Reduce Neuropathic Pain in Chronic Spinal Cord Injury

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2021-02-01

Completion:

2024-03-31

Conditions

• Spinal Cord Injuries

Interventions

• DRUG
• OTHER

Results Available

NCT04363957 | COMPLETED | NA

80 participants

Gynecologic Brachytherapy-Specific Educational Video

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2020-04-01

Completion:

2022-04-22

Conditions

• Cervical Cancer
• Uterine Cancer

Interventions

• OTHER

Results Available

NCT04341064 | COMPLETED | PHASE3

2223 participants

Sun-safe Habits Intervention and Education

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2020-09-14

Completion:

2025-07-15

Conditions

• Skin Cancer
• Adolescents

Interventions

• BEHAVIORAL

No Results Yet

NCT04338776 | ACTIVE_NOT_RECRUITING | NA

120 participants

Comparing UroLift Experience Against Rezūm

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2021-01-22

Completion:

2025-06-05

Conditions

• Benign Prostatic Hyperplasia

Interventions

• DEVICE

No Results Yet

NCT04201288 | COMPLETED | NA

38 participants

Brief Acceptance-Based Retention Intervention for Newly Diagnosed HIV Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2020-12-21

Completion:

2025-03-31

Conditions

• HIV/AIDS

Interventions

• BEHAVIORAL

Results Available

NCT04201262 | COMPLETED | PHASE3

58 participants

An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2019-12-09

Completion:

2022-03-15

Conditions

• Neuromyelitis Optica
• Neuromyelitis Optica Spectrum Disorder

Interventions

• BIOLOGICAL

Results Available

NCT04144790 | COMPLETED

12 participants

Impact of Iron Supplementation Treatment on Brain Iron Concentrations

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-14

Start Date:

2022-09-15

Completion:

2025-06-30

Conditions

• ADHD
• Iron-deficiency
• Restless Legs Syndrome
• Periodic Limb Movement Sleep Disorder

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04117958 | TERMINATED | PHASE1

58 participants

Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2020-01-20

Completion:

2023-06-01

Conditions

• MUC17-positive Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04106414 | ACTIVE_NOT_RECRUITING | PHASE2

24 participants

Study of BMS-986205 and Nivolumab in Endometrial Cancer or Endometrial Carcinosarcoma That Has Not Responded to Treatment

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2019-09-24

Completion:

2026-09-30

Conditions

• Endometrial Adenocarcinoma
• Endometrial Carcinosarcoma

Interventions

• DRUG

No Results Yet

NCT04103892 | COMPLETED | PHASE2

146 participants

A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2019-09-05

Completion:

2022-09-21

Conditions

• Adjunctive Treatment of Major Depressive Disorder

Interventions

• DRUG

Results Available

NCT04079868 | COMPLETED | NA

3512 participants

Models of Primary Osteoporosis Screening in Male Veterans

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2019-08-30

Completion:

2024-08-31

Conditions

• Osteoporosis
• Osteopenia
• Osteoporotic Fracture

Interventions

• BEHAVIORAL

Results Available

NCT04036305 | ACTIVE_NOT_RECRUITING

230 participants

Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy Volunteers

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-14

Start Date:

2019-07-26

Completion:

2029-12-31

Conditions

• Ehlers-Danlos Syndrome
• Anesthesia, Local

Interventions

• DRUG

No Results Yet

NCT04036032 | COMPLETED

47 participants

Role of Aerobic Exercise to Modulate Cardiotoxicity in Long Term Cancer Survivors Exposed to Anthracycline Therapy

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-14

Start Date:

2015-06-19

Completion:

2025-08-27

Conditions

• Cancer
• Cardiotoxicity

Interventions

• OTHER

No Results Yet

NCT04033510 | ACTIVE_NOT_RECRUITING

600 participants

Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-14

Start Date:

2019-08-14

Completion:

2024-11-25

Conditions

• Atrial Fibrillation
• Cognitive Symptom
• Executive Dysfunction
• Cognitive Change
• Cognitive Impairment
• Cognitive Impairment, Mild

Interventions

• OTHER

No Results Yet

NCT03945825 | COMPLETED | PHASE1

241 participants

Flublok or Fluzone With Advax-CpG55.2 or AF03

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2019-06-10

Completion:

2020-09-18

Conditions

• Influenza
• Influenza Immunisation

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT03939689 | COMPLETED | PHASE2

120 participants

I-131-1095 Radioligand Plus Enzalutamide vs Enzalutamide for mCRPC That Progressed During Abiraterone (ARROW).

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2019-05-30

Completion:

2023-09-21

Conditions

• Metastatic Prostate Cancer
• Castration-resistant Prostate Cancer
• Prostatic Neoplasm
• Cancer of the Prostate
• Progressive mCRPC

Interventions

• DRUG

Results Available

NCT03874754 | COMPLETED | NA

34 participants

Tailored Home-Based Exercise Program for Multiple Chronic Conditions

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2019-08-01

Completion:

2021-01-31

Conditions

• Cancer
• Hypertension
• Diabetes

Interventions

• OTHER

Results Available

NCT03651700 | COMPLETED | PHASE2

86 participants

Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2019-03-28

Completion:

2024-08-31

Conditions

• Aphasia

Interventions

• DEVICE
• BEHAVIORAL

Results Available

NCT03620058 | ACTIVE_NOT_RECRUITING | PHASE1

23 participants

CART22 Alone or in Combination With huCART19 for ALL

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2018-09-27

Completion:

2036-01-31

Conditions

• Chemotherapy Resistant Acute Lymphoblastic Leukemia
• Refractory Acute Lymphoblastic Leukemia

Interventions

• BIOLOGICAL

No Results Yet

NCT03573947 | COMPLETED | PHASE2

46 participants

Phase II Clinical Trial of NIVO-IPI-TAXANE in Untreated Metastatic NSCLC

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2018-10-02

Completion:

2023-03-12

Conditions

• Non-small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT03515512 | COMPLETED | PHASE1

23 participants

IDH2 Inhibition Using Enasidenib as Maintenance Therapy for IDH2-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2018-07-17

Completion:

2021-12-31

Conditions

• Acute Myeloid Leukemia
• Chronic Myelomonocytic Leukemia

Interventions

• DRUG

No Results Yet

NCT03430583 | COMPLETED | PHASE3

88 participants

Evaluation of Fontan-associated Hepatic Stiffness and the Efficacy of Udenafil in Reducing Liver Stiffness

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2018-02-20

Completion:

2020-09-15

Conditions

• Single Ventricle Heart Disease

Interventions

• DRUG

Results Available

NCT03412916 | COMPLETED | NA

82 participants

Integrating Mind-Body Skills With Physical Activity to Improve Physical and Emotional Outcomes in Patients With Chronic Pain

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2017-10-01

Completion:

2020-06-30

Conditions

• Pain
• Chronic Pain
• Physical Activity

Interventions

• BEHAVIORAL

Results Available

NCT03412773 | COMPLETED | PHASE3

684 participants

A Study of Tislelizumab Versus Sorafenib in Participants With Unresectable Hepatocellular Carcinoma (HCC)

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2017-12-18

Completion:

2022-07-11

Conditions

• Hepatocellular Carcinoma (HCC)

Interventions

• DRUG

Results Available

NCT03345576 | COMPLETED | PHASE2

12 participants

Testosterone and Long Pulse Stimulation After SCI

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2018-07-01

Completion:

2023-06-30

Conditions

• Spinal Cord Injury

Interventions

• DEVICE
• DRUG

Results Available

NCT03219502 | ACTIVE_NOT_RECRUITING | NA

56 participants

rTMS in Improving Neuropathy in Patients With Stage I-IV Cancer Who Have Received Oxaliplatin Chemotherapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2017-07-10

Completion:

2027-04-30

Conditions

• Malignant Neoplasm
• Neuropathy

Interventions

• OTHER
• PROCEDURE

No Results Yet

NCT03218761 | ACTIVE_NOT_RECRUITING

200 participants

POTS NET mRNA Functional Correlation With NET Activity

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-14

Start Date:

2017-07-14

Completion:

2029-12-31

Conditions

• Postural Tachycardia Syndrome

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03099850 | RECRUITING

2345 participants

Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies

Study Type:

OBSERVATIONAL

Last Updated:

2025-10-14

Start Date:

2017-02-28

Completion:

2030-06-30

Conditions

• Pancreatitis

Interventions

• OTHER

No Results Yet

NCT03083665 | COMPLETED | PHASE3

449 participants

A Study to Evaluate the Efficacy and Safety of Brivaracetam in Study Participants (>=16 to 80 Years of Age) With Epilepsy

Study Type:

INTERVENTIONAL

Last Updated:

2025-10-14

Start Date:

2017-08-22

Completion:

2022-06-30

Conditions

• Partial Seizures With or Without Secondary Generalization
• Epilepsy

Interventions

• DRUG

Results Available