Clinical Trials Updated in 2025

NCT04462419 | TERMINATED

19 participants

18F-fluciclovine PET/MRI Imaging for the Detection of Tumor Recurrence After Radiation Injury to the Brain

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-08-18
Completion:: 2023-12-13

Conditions

Metastatic Intracranial Malignant Neoplasm
Recurrent Intracranial Neoplasm

Interventions

RADIATION
OTHER

No Results Yet

NCT04411849 | COMPLETED | NA

802 participants

Multilevel HPV Self-Testing Intervention for the Increase of Cervical Cancer Screening Among Women in Appalachia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-08-27
Completion:: 2024-06-11

Conditions

Cervical Carcinoma
Human Papillomavirus Infection

Interventions

OTHER
PROCEDURE
BEHAVIORAL

Results Available

NCT04374630 | COMPLETED | PHASE2

150 participants

Study With Afuresertib and Paclitaxel in Platinum Resistant Ovarian

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-06-09
Completion:: 2023-07-31

Conditions

Platinum-resistant Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT04358692 | COMPLETED | NA

98 participants

Measurement of Myocardial Stiffness Using Elastometry in Patients With Aortic Stenosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-06-30
Completion:: 2024-06-14

Conditions

Aortic Valve Stenosis

Interventions

DEVICE

No Results Yet

NCT04327973 | AVAILABLE

Expanded Access for ATB200/AT2221 for the Treatment of IOPD

Study Type:: EXPANDED_ACCESS
Last Updated:: 2025-09-10

Conditions

Pompe Disease Infantile-Onset

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04296604 | RECRUITING | NA

600 participants

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2014-09-30
Completion:: 2026-04-30

Conditions

Traumatic Brain Injury
Major Depressive Disorder
Bipolar Disorder
Schizophrenia
Attention Deficit Hyperactivity Disorder
Borderline Personality Disorder
Substance Use Disorders

Interventions

DEVICE

No Results Yet

NCT04273542 | ACTIVE_NOT_RECRUITING | NA

1100 participants

Interest of Broadband Spectroscopy Analysis by Infrared Laser on Liquid Biopsies in Breast Cancer Screening

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-05-31
Completion:: 2029-05-31

Conditions

Breast Cancer Female
BRCA1 Mutation
BRCA2 Mutation

Interventions

OTHER

No Results Yet

NCT04270747 | COMPLETED | PHASE3

576 participants

A Study to Understand Effectiveness and Safety of ABP 938 Compared to Aflibercept (Eylea®) in Patients Suffering With Neovascular Age-related Macular Degeneration [Neovascular (Wet) AMD]

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-06-22
Completion:: 2022-07-18

Conditions

Neovascular (Wet) Age-related Macular Degeneration (AMD)

Interventions

DRUG

Results Available

NCT04234724 | RECRUITING | NA

50 participants

Physiological Effects of ANGPTL3 Variants in Humans

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-12-01
Completion:: 2026-06-30

Conditions

Hypocholesterolemia

Interventions

OTHER

No Results Yet

NCT04233372 | COMPLETED | PHASE4

399 participants

Evaluation of (Doravirine / Lamivudine / Tenofovir Disoproxil Fumarate) (Delstrigo®) as a New Strategy for Non-occupational Post Exposure Prophylaxis, a Prospective Open Label Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-08-27
Completion:: 2022-07-28

Conditions

Hiv

Interventions

DRUG

Results Available

NCT04226365 | TERMINATED | PHASE4

8 participants

Pediatric Concussion Outcomes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-02-15
Completion:: 2023-05-31

Conditions

Concussion Post Syndrome
Headaches Posttraumatic
Mild Traumatic Brain Injury

Interventions

DRUG

Results Available

NCT04130802 | COMPLETED | PHASE2

153 participants

OCS-01 in Treating Inflammation and Pain in Post-cataract Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-09-27
Completion:: 2020-01-31

Conditions

Inflammation Corneal
Pain, Postoperative

Interventions

DRUG

Results Available

NCT04119388 | COMPLETED | NA

30 participants

Evaluation of the Benefits of Adaptive Physical Activity in Children and Adolescents With Osteogenesis Imperfecta

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-11-04
Completion:: 2022-10-14

Conditions

Osteogenesis Imperfecta

Interventions

OTHER

No Results Yet

NCT04108052 | COMPLETED | NA

45 participants

Diagnostic Value of Ultra-low Dose Thoracic Scanner for the Pulmonary Arteriovenous Malformation Detection in HHT Patient

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-11-28
Completion:: 2021-05-28

Conditions

Telangiectasia, Hereditary Hemorrhagic
Rendu Osler Disease

Interventions

RADIATION

No Results Yet

NCT04081220 | ACTIVE_NOT_RECRUITING | PHASE2

9 participants

Hematology, IMG-7289, LSD1 (Lysine-Specific Demethylase 1) Inhibitor, Essential Thrombocythemia (ET), Ph 2

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-04-09
Completion:: 2023-12-20

Conditions

Thrombocythemia, Essential

Interventions

DRUG

Results Available

NCT04057690 | ACTIVE_NOT_RECRUITING

1687 participants

Automatic PredICtion of Edema After Stroke

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-04-01
Completion:: 2023-09-30

Conditions

Stroke, Acute
Brain Edema

No Results Yet

NCT04024631 | RECRUITING | NA

100 participants

Phenotyping Genetic Risk for Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-06-17
Completion:: 2026-06-30

Conditions

Diabetes Mellitus, Type 2
Genetics

Interventions

OTHER

No Results Yet

NCT04018248 | COMPLETED | PHASE1

26 participants

BR101801 in Adult Patients With Advanced Hematologic Malignancies(Phase I)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-04-21
Completion:: 2023-09-21

Conditions

Diffuse Large B Cell Lymphoma
Follicular Lymphoma
Chronic Lymphocytic Leukemia
Small Lymphocytic Leukemia
B Cell Lymphoma
Marginal Zone Lymphoma
Waldenstrom Macroglobulinemia
Peripheral T Cell Lymphoma

Interventions

DRUG

No Results Yet

NCT03948074 | COMPLETED | PHASE2

91 participants

Cannabis For Cancer-Related Symptoms

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-02-01
Completion:: 2025-07-23

Conditions

Pain
Nausea
Anxiety
Sleep Disturbance

Interventions

DRUG

No Results Yet

NCT03937219 | ACTIVE_NOT_RECRUITING | PHASE3

855 participants

Study of Cabozantinib in Combination With Nivolumab and Ipilimumab in Patients With Previously Untreated Advanced or Metastatic Renal Cell Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-06-25
Completion:: 2022-01-31

Conditions

Renal Cell Carcinoma

Interventions

DRUG
BIOLOGICAL

Results Available

NCT03924778 | NOT_YET_RECRUITING | NA

28 participants

Modifying Diet to Improve Gut Microbiome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2026-07-31
Completion:: 2026-08-31

Conditions

Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT03881696 | COMPLETED | PHASE3

471 participants

Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-07-22
Completion:: 2023-03-13

Conditions

Peanut Allergy
Multi-food Allergy

Interventions

DRUG
OTHER

Results Available

NCT03871348 | TERMINATED | PHASE1

77 participants

A First-in-Human Dose Escalation and Expansion Study to Evaluate Intratumoral Administration of SAR441000 as Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-01-03
Completion:: 2022-07-25

Conditions

Metastatic Neoplasm

Interventions

DRUG

No Results Yet

NCT03843918 | TERMINATED | PHASE1/PHASE2

33 participants

A Study on the Safety and Efficacy of LAE001 in the Treatment of Metastatic Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-04-05
Completion:: 2023-10-09

Conditions

Prostate Cancer Metastatic

Interventions

DRUG

No Results Yet

NCT03815019 | COMPLETED | PHASE4

70 participants

iKanEat: A Randomized-controlled, Multi-center Trial of Megestrol for Chronic Oral Food Refusal in Children

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-08-15
Completion:: 2025-03-19

Conditions

Feeding Behavior
Feeding Disorder of Infancy or Early Childhood

Interventions

DRUG
BEHAVIORAL

Results Available

NCT03809273 | COMPLETED | PHASE4

681 participants

Effects of Yangxinshi Pills on the Exercise Tolerance Compared With Trimetazidine in Patients After PCI

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-08-01
Completion:: 2020-12-31

Conditions

Percutaneous Coronary Intervention

Interventions

DRUG

No Results Yet

NCT03797482 | RECRUITING

500 participants

A Prospective Evaluation of the Peri-operative Hypoxia in Breast Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-10
Start Date:: 2017-11-27
Completion:: 2025-09-30

Conditions

Breast Cancer Female

Interventions

PROCEDURE

No Results Yet

NCT03775460 | ACTIVE_NOT_RECRUITING | NA

550 participants

Methotrexate and Prednisolone Study in Erythema Nodosum Leprosum

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2023-01-15
Completion:: 2025-09-01

Conditions

Erythema Nodosum Leprosum

Interventions

DRUG

No Results Yet

NCT03773367 | ACTIVE_NOT_RECRUITING | PHASE2

60 participants

Irinotecan-based Triplet (FOLFOXIRI) as Perioperative Treatment in Resectable Gastric and Gastroesophageal Junction Adenocarcinoma.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2018-12-14
Completion:: 2026-11-30

Conditions

Resectable Gastric and Gastroesophageal Junction Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT03763643 | COMPLETED | EARLY_PHASE1

21 participants

PRI-VENT FSGS: Preemptive Rituximab to Prevent Recurrent Focal Segmental Glomerulosclerosis Post-Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-07-01
Completion:: 2025-02-07

Conditions

Focal Segmental Glomerulosclerosis

Interventions

DRUG
PROCEDURE

No Results Yet

NCT03759834 | COMPLETED | NA

25 participants

Cochlear Promontory Stimulation for Treatment of Tinnitus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2018-01-04
Completion:: 2024-08-13

Conditions

Tinnitus

Interventions

DEVICE

Results Available

NCT03726788 | WITHDRAWN | PHASE2

0 participants

Intra Articular Injection of Botulinum Toxin Versus Corticoids in Gonarthrosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-09-30
Completion:: 2021-11-30

Conditions

Joint Diseases
Knee
Therapeutics
Magnetic Resonance Imaging

Interventions

DRUG

No Results Yet

NCT03707288 | RECRUITING | NA

1000 participants

Neck and Low Back Pain in Medical Students at The University of the West Indies, Mona, Jamaica

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2018-10-01
Completion:: 2026-01-02

Conditions

Back Pain
Low Back Pain
Neck Pain
Neck Pain Musculoskeletal
Lower Back Pain
Spine Health
Musculoskeletal Pain
Musculoskeletal Pain Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT03654742 | ACTIVE_NOT_RECRUITING | NA

167 participants

Intracapsular Tonsillectomy in Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-09-27
Completion:: 2023-01-05

Conditions

Tonsil Disease
Tonsillitis
Tonsillitis Acute
Tonsillitis Chronic

Interventions

PROCEDURE

No Results Yet

NCT03653546 | COMPLETED | PHASE2/PHASE3

492 participants

First Line Treatment in EGFR Mutation Positive Advanced NSCLC Patients With Central Nervous System (CNS) Metastases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2018-10-29
Completion:: 2022-07-12

Conditions

Non-small Cell Lung Cancer
EGFR Gene Mutation
Brain Metastases

Interventions

DRUG

No Results Yet

NCT03627013 | RECRUITING | PHASE3

362 participants

Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-05-23
Completion:: 2028-09-30

Conditions

Kidney Failure
Liver Failure, Chronic
Kidney-Pancreas Failure

Interventions

DRUG

No Results Yet

NCT03508739 | SUSPENDED | PHASE3

25 participants

Glucagon-like Peptide-1 Metabolism and Acute Neprilysin Inhibition

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2018-06-01
Completion:: 2026-06-01

Conditions

Diabetes Mellitus, Type 2
Pre-diabetic
Hypertension
Elevated Blood Pressure

Interventions

DRUG

No Results Yet

NCT03501303 | COMPLETED | NA

902 participants

A Clinical Trial on No-touch Vein Graft (NT-graft) in Coronary Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2018-04-20
Completion:: 2023-09-19

Conditions

Ischemic Heart Disease

Interventions

PROCEDURE

No Results Yet

NCT03466918 | COMPLETED | NA

58 participants

China S3: Safety and Effectiveness of Edwards Lifesciences SAPIEN 3 THV in the Chinese Population

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2018-05-23
Completion:: 2019-07-03

Conditions

Aortic Stenosis
Symptomatic Aortic Stenosis
Aortic Regurgitation

Interventions

DEVICE

Results Available

NCT03459287 | COMPLETED | PHASE3

581 participants

Study to Evaluate the Efficacy & Safety of the INTERCEPT Blood System for RBCs in Complex Cardiac Surgery Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2018-12-05
Completion:: 2023-12-04

Conditions

Anemia

Interventions

DEVICE

Results Available