Physiological Effects of ANGPTL3 Variants in Humans

NCT04234724 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2025-09-10

No results posted yet for this study

Summary

To evaluate the role of ANGPTL3, on lipid metabolism. To explore the role of this protein on glucose metabolism.

Conditions

  • Hypocholesterolemia

Interventions

OTHER

Kinetics test, oral fat tolerance test, and an oral glucose tolerance test.

Subjects will participate in a kinetics test, oral fat tolerance test, and an oral glucose tolerance test.

Sponsors & Collaborators

Principal Investigators

  • Marina Cuchel, MD, PhD · University of Pennsylvania

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-12-01
Primary Completion
2026-06-30
Completion
2026-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04234724 on ClinicalTrials.gov