Physiological Effects of ANGPTL3 Variants in Humans
NCT04234724 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2025-09-10
Summary
To evaluate the role of ANGPTL3, on lipid metabolism. To explore the role of this protein on glucose metabolism.
Conditions
- Hypocholesterolemia
Interventions
- OTHER
-
Kinetics test, oral fat tolerance test, and an oral glucose tolerance test.
Subjects will participate in a kinetics test, oral fat tolerance test, and an oral glucose tolerance test.
Sponsors & Collaborators
-
National Heart, Lung, and Blood Institute (NHLBI)
collaborator NIH - lead OTHER
Principal Investigators
-
Marina Cuchel, MD, PhD · University of Pennsylvania
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2020-12-01
- Primary Completion
- 2026-06-30
- Completion
- 2026-06-30
Countries
- United States
Study Locations
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