Clinical Trials Updated in 2025

NCT04949646 | RECRUITING | NA

44 participants

Intraoperative Neuromonitoring of Pelvic Autonomous Nerve Plexus During Total Mesorectal Excision

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-09-19
Completion:: 2027-09-19

Conditions

Rectal Neoplasms

Interventions

OTHER

No Results Yet

NCT04915820 | COMPLETED | NA

121 participants

Iron and COVID-19 Vaccine Response

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-05-29
Completion:: 2021-09-09

Conditions

Iron Deficiency Anemia
Vaccine Response Impaired
COVID-19 Vaccine
Iron Deficiency Anemia Treatment

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04893460 | COMPLETED | NA

72 participants

CoQuit Study for Smoking Cessation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-06-01
Completion:: 2021-09-29

Conditions

Smoking Cessation

Interventions

BEHAVIORAL

Results Available

NCT04879849 | COMPLETED | PHASE1

34 participants

A Study of TAK-676 With Pembrolizumab After Radiation Therapy to Treat a Number of Cancers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-09-09
Completion:: 2024-04-30

Conditions

Carcinoma, Non-Small-Cell Lung
Triple Negative Breast Neoplasms
Squamous Cell Carcinoma of Head and Neck

Interventions

DRUG
RADIATION

Results Available

NCT04866004 | COMPLETED | NA

25 participants

Contingency Management for Cannabis Use for Persons With HIV

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-08-01
Completion:: 2025-07-31

Conditions

Marijuana
HIV Infections

Interventions

BEHAVIORAL

No Results Yet

NCT04813731 | COMPLETED

300 participants

COVID-19 And Lingering Symptoms In Primary Care Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-12-12
Completion:: 2022-06-30

Conditions

Covid19
Symptoms and Signs

No Results Yet

NCT04808986 | COMPLETED | NA

2817 participants

Seroprevalence of IgG Antibodies to SARS-CoV-2 (COVID-19) in Primary Health Care Workers and Their Household Contacts

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-05-10
Completion:: 2021-10-12

Conditions

Covid19

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04777864 | COMPLETED | NA

110 participants

Developing a Tool to Support Shared Decision Making Post-Concussion Between Adolescents, Parents and Clinicians

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-08-30
Completion:: 2024-04-01

Conditions

Concussion, Brain

Interventions

BEHAVIORAL

Results Available

NCT04759976 | COMPLETED | NA

259 participants

Optimize Motor Learning to Improve Neurorehabilitation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2019-01-25
Completion:: 2024-04-15

Conditions

Stroke
Neurologic Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT04726618 | TERMINATED

24 participants

Development of Hardware and Software for Pulmonary Magnetic Resonance Imaging Using Inhaled Tracer Gases

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-04
Start Date:: 2022-03-01
Completion:: 2024-04-09

Conditions

Healthy Volunteers

Interventions

DRUG

No Results Yet

NCT04694534 | RECRUITING | NA

150 participants

Remediation Program Via a "Serious Game" for the Cognitive Functions of Multiple Sclerosis Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-10-08
Completion:: 2026-04-04

Conditions

Multiple Sclerosis
Memory
Learning

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04683627 | COMPLETED | PHASE3

370 participants

A 12-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Osteoarthritis Pain of the Knee

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-12-29
Completion:: 2022-07-18

Conditions

Osteoarthritis Pain of the Knee

Interventions

DRUG

Results Available

NCT04669496 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

178 participants

Phase II-III Clinical Trial of PD1 Antibody (Toripalimab), Lenvatinib and GEMOX Neoadjuvant Treatment for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence Factors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-01-20
Completion:: 2025-04-30

Conditions

Intrahepatic Cholangiocarcinoma
PD1 Antibody
Lenvatinib
Gemox Chemotherapy

Interventions

DRUG

No Results Yet

NCT04666792 | COMPLETED | PHASE4

25457 participants

PrEParing Family Planning Clinics to Streamline Integration of HIV Prevention Services for Young Women in Kenya

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-03-01
Completion:: 2024-12-31

Conditions

HIV Infections
Contraception
STI

Interventions

DRUG

No Results Yet

NCT04557709 | WITHDRAWN

0 participants

Major Complication Rate in Cancer Patients With Neutropenic Fever Potentially Eligible for a Hospital at Home Program

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-07-13
Completion:: 2024-11-18

Conditions

Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm

Interventions

OTHER

No Results Yet

NCT04538612 | COMPLETED | NA

20 participants

DiCART TM Device for Capillary Refill Time Measurement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-01-28
Completion:: 2020-07-10

Conditions

Peripheral Perfusion

Interventions

DEVICE

No Results Yet

NCT04440839 | COMPLETED | NA

116 participants

Implementation of Telemedicine for Patient With Lower Extremity Wounds

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-03-01
Completion:: 2023-11-01

Conditions

Peripheral Arterial Disease
Peripheral Artery Disease
Peripheral Vascular Diseases
Diabetic Foot
Diabetic Foot Ulcer
Diabetic Foot Infection
Diabetic Peripheral Neuropathy

Interventions

OTHER

Results Available

NCT04427280 | COMPLETED

153 participants

Cancer: Rapid Diagnostics and Immune Assessment for SARS-CoV-2 (COVID-19)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-05-26
Completion:: 2021-06-29

Conditions

Infectious Disease
Cancer
Coronavirus Infection

Interventions

DIAGNOSTIC_TEST

Results Available

NCT04405557 | ACTIVE_NOT_RECRUITING

757 participants

The PREDICT Study: Prospective Early Detection In a Population at High-risk for Common Malignant Tumor

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-04
Start Date:: 2019-11-12
Completion:: 2022-01-16

Conditions

Early Detection of Cancer

No Results Yet

NCT04396288 | COMPLETED | NA

19 participants

Ultrasound Imaging-based Measurement of Intra-osseous Vascular Response

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-09-14
Completion:: 2022-12-14

Conditions

Blood Circulation Disorder
Bone Diseases, Metabolic

Interventions

DEVICE

No Results Yet

NCT04388163 | WITHDRAWN | PHASE2

0 participants

Gentian Violet Treatment for Hidradenitis Suppurativa

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2025-08-31
Completion:: 2026-12-31

Conditions

Hidradenitis Suppurativa

Interventions

DRUG

No Results Yet

NCT04384627 | ACTIVE_NOT_RECRUITING | PHASE3

445 participants

Reducing Target Volumes in NPC Treated With Induction Chemotherapy Followed by Concurrent Chemoradiotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2019-12-01
Completion:: 2024-08-20

Conditions

Nasopharyngeal Carcinoma
Induction Chemotherapy
Radiotherapy

Interventions

RADIATION

No Results Yet

NCT04358575 | COMPLETED | NA

60 participants

Migration and Survival of All-polyethylene Tibial All Poly Components Compared to the Metal-backed Modular Components of the Triathlon CS Total Knee System. A Single Center RSA Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2014-02-28
Completion:: 2014-10-31

Conditions

Arthritis

Interventions

DEVICE

No Results Yet

NCT04325282 | COMPLETED | NA

22 participants

Transcranial Magnetic Stimulation for BECTS

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-10-28
Completion:: 2024-03-03

Conditions

Benign Epilepsy With Centrotemporal Spikes
Language Problems
Learning Disorders

Interventions

DEVICE

Results Available

NCT04324450 | COMPLETED | NA

60 participants

Memory Neuroimaging in Children, Adolescents and Young Adults Following Pediatric Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-02-12
Completion:: 2021-08-19

Conditions

Cancer Brain
Pediatric Cancer

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT04314141 | COMPLETED

143 participants

Surgical Outcomes, Quality of Life and Patient's Satisfactions With Phalloplasty

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-05-15
Completion:: 2020-11-14

Conditions

Phalloplasty
Surgery

Interventions

PROCEDURE

No Results Yet

NCT04308590 | COMPLETED | PHASE3

137 participants

A Study of the Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-07-27
Completion:: 2024-09-19

Conditions

Hypercortisolism

Interventions

DRUG
OTHER

Results Available

NCT04306536 | TERMINATED | NA

20 participants

Nutritional Support in Femur Fracture Rehabilitation

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-06-19
Completion:: 2020-12-20

Conditions

Femur Fracture

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04265144 | RECRUITING | NA

500 participants

Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference Centre

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-06-08
Completion:: 2034-06-30

Conditions

Scleroderma
Systemic Sclerosis

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT04235517 | RECRUITING

10 participants

RSA Study on the Behaviour of the Growth Plate During and After Temporary Hemi-epiphysiodesis and Epiphysiodesis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-04
Start Date:: 2017-01-31
Completion:: 2027-01-31

Conditions

Anisomelia
Deformity of Limb

Interventions

OTHER

No Results Yet

NCT04218773 | SUSPENDED | EARLY_PHASE1

40 participants

Blood PREssure Augmentation in Large-vessel Occlusion Stroke Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-09-11
Completion:: 2026-08-31

Conditions

Ischemic Stroke
Blood Pressure

Interventions

DRUG

No Results Yet

NCT04191616 | COMPLETED | PHASE2

54 participants

Study of Early Relapsed, Lenalidomide-refractory Subjects Eligible for Carfilzomib Triplet

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-08-06
Completion:: 2022-11-30

Conditions

Relapsed or Refractory Multiple Myeloma

Interventions

DRUG

Results Available

NCT04187326 | COMPLETED | NA

23 participants

Assessing Visual Processing in High Anxiety

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-03-01
Completion:: 2024-03-15

Conditions

Anxiety

Interventions

BEHAVIORAL

Results Available

NCT04153331 | COMPLETED | NA

2487 participants

Burden of Influenza at Emergency Department Level : BIED

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2020-01-13
Completion:: 2020-03-09

Conditions

Emergencies
Flu

Interventions

OTHER

No Results Yet

NCT04136717 | RECRUITING | NA

10 participants

Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2019-10-28
Completion:: 2027-07-31

Conditions

COPD Exacerbation
Oxygen Toxicity
Abdominal Obesity
Surgery

Interventions

OTHER
DEVICE

No Results Yet

NCT04098146 | RECRUITING

300 participants

Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-04
Start Date:: 2022-09-12
Completion:: 2030-06-30

Conditions

Mandibular Reconstruction
Segmental Mandibular Defects

Interventions

PROCEDURE

No Results Yet

NCT04092530 | COMPLETED | NA

2518 participants

Linking Inter-professional Newborn and Contraception Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2021-04-01
Completion:: 2023-06-30

Conditions

Family Planning
Contraception
PostPartum

Interventions

BEHAVIORAL

Results Available

NCT04078997 | COMPLETED

3507 participants

An Evaluation of PCV13 Vaccine Schedules, Comparing Impact of 2+1 vs 3+0 on Pneumococcal Carriage in Blantyre, Malawi

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-04
Start Date:: 2019-07-21
Completion:: 2024-02-16

Conditions

13-valent Pneumococcal Vaccine
Streptococcus Pneumoniae

Interventions

OTHER

No Results Yet

NCT04078763 | COMPLETED | NA

12 participants

Rehabilitation of the Auditory Space for Bilateral Cochlear Implant Users : a Feasibility Study

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2019-10-25
Completion:: 2020-09-04

Conditions

Cochlear Prosthesis Implantation

Interventions

BEHAVIORAL

No Results Yet

NCT04078698 | COMPLETED | NA

34 participants

Documentation of the Safety and Effectiveness Profile of the IgG Immunoadsorber GLOBAFFIN® in Clinical Routine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-04
Start Date:: 2019-09-05
Completion:: 2025-05-30

Conditions

Autoimmune Diseases

Interventions

DEVICE

No Results Yet