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Reducing Target Volumes in NPC Treated With Induction Chemotherapy Followed by Concurrent Chemoradiotherapy

NCT04384627 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 445

Last updated 2025-09-04

No results posted yet for this study

Summary

To evaluate the long-term locoregional control, survival rate, late toxicity and quality of life after reducing the target volume in patients with locoregionally advanced nasopharyngeal carcinoma patients treated with induction chemotherapy plus concurrent chemoradiotherapy.

Conditions

  • Nasopharyngeal Carcinoma
  • Induction Chemotherapy
  • Radiotherapy

Interventions

RADIATION

Delineating the GTV according to the pretreatment or post-IC tumor extension

Delineating the GTV according to the pretreatment or post-IC tumor extension

Sponsors & Collaborators

  • First People's Hospital of Foshan

    collaborator OTHER

  • Cancer Research Institute of Zhongshan City

    collaborator OTHER_GOV

  • Sun Yat-sen University

    lead OTHER

Principal Investigators

  • Ling-Long Tang · Sun Yat-sen University Cancer Centr

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-12-01
Primary Completion
2024-08-20
Completion
2026-10-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04384627 on ClinicalTrials.gov