Clinical Trials Updated in 2021

NCT00000958 | COMPLETED | PHASE1

8 participants

A Placebo-Controlled, Phase I, Pilot Clinical Trial to Evaluate the Safety and Immunogenicity of ENV 2-3, a Yeast-Derived Recombinant Envelope Protein of Human Immunodeficiency Virus-1, in Combination With MTP-PE/MF59 in Individuals With HIV Infection (Placebo Patients Receive MF59 Emulsion Only)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000957 | COMPLETED | PHASE1

30 participants

A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia Derived HIV-1 Recombinant Envelope Glycoprotein (gp160) of Human Immunodeficiency Virus: Evaluation of Accelerated Schedules

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000956 | COMPLETED | PHASE1

25 participants

A Phase I Multicenter Trial to Evaluate the Safety and Immunogenicity of HIV-1 Recombinant Envelope Glycoprotein gp160

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000906 | COMPLETED | PHASE1

12 participants

Interactions of HIV Protease Inhibitors and Methadone in HIV-Infected Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000904 | COMPLETED | PHASE1

100 participants

Safety and Effectiveness of Anti-HIV Vaccines in HIV-Negative Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000892 | COMPLETED | NA

300 participants

A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used Indinavir

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000891 | COMPLETED | PHASE2

34 participants

Immunologic and Virologic Consequences of Long-Term Highly Active Antiretroviral Therapy (HAART) in Subjects With Moderately Advanced HIV-1 Disease: A Follow-Up Study to ACTG 315

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000872 | COMPLETED | PHASE2

55 participants

Treatment With Combinations of Several Antiviral Drugs in Infants and Young Children With HIV Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000871 | COMPLETED | PHASE2

420 participants

A Phase II Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV vCP205 With or Without HIV-1 SF-2 RGP120 in HIV-1 Uninfected Adult Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000853 | COMPLETED | PHASE1

37 participants

A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of Low Dose MN rsgp120/HIV-1 (Genentech) in Combination With QS21 Adjuvant or Alum in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000851 | COMPLETED | PHASE2

198 participants

Comparison of Stavudine Used Alone or in Combination With Didanosine in HIV-Infected Children

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000848 | COMPLETED | PHASE2

144 participants

The Anti-HIV Effects of Saquinavir Soft Gelatin Capsules Versus Indinavir in Patients Who Have Used Saquinavir Hard Gelatin Capsules for One Year

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000847 | COMPLETED | PHASE1

150 participants

A Phase I Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV (vCP205) and HIV-1 SF-2 rgp120 in HIV-1 Uninfected Adult Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000842 | COMPLETED | PHASE2

270 participants

A Phase II, Double-Blind Trial of Recombinant Human Nerve Growth Factor for Treatment of HIV-Associated Sensory Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections
Peripheral Nervous System Disease

Interventions

DRUG

No Results Yet

NCT00000841 | COMPLETED | PHASE3

1750 participants

A Study of Indinavir Sulfate Plus Zidovudine (AZT) Plus Lamivudine in HIV-Infected Patients Who Have Taken AZT for Six or More Months

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000838 | COMPLETED | PHASE2

256 participants

Antiviral Activity of and Resistance to Lamivudine in Combination With Zidovudine, Stavudine, or Didanosine

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000832 | COMPLETED | PHASE1

30 participants

A Randomized, Placebo-Controlled, Double-Blinded Phase I Safety and Immunogenicity Trial of Recombinant Envelope Protein, HIV-1 SF-2 rgp120 (BIOCINE), Combined With MF59 in HIV-1 Uninfected Adult Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000831 | COMPLETED | PHASE2

280 participants

Virologic Responses To New Nucleoside Regimens After Prolonged ZDV or ddI Monotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000827 | COMPLETED | PHASE1

45 participants

A Phase I/II Study of Hyperimmune IVIG in Slowing Progression of Disease in HIV-Infected Children

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000816 | COMPLETED | PHASE4

370 participants

Gradual Initiation of Sulfamethoxazole/Trimethoprim as Primary Pneumocystis Carinii Pneumonia Prophylaxis

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

Pneumonia, Pneumocystis Carinii
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000813 | COMPLETED | PHASE1

28 participants

A Phase I Safety and Immunogenicity Trial of Live Recombinant Canarypox-gp160 MN (ALVAC vCP125, HIV-1 gp160 MN) in HIV-1 Uninfected Adult Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000811 | COMPLETED | PHASE2

690 participants

A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

Bacterial Infections
Pneumonia, Pneumocystis Carinii
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000810 | COMPLETED | PHASE1

120 participants

Randomized, Phase I/II, Dose-Ranging, Open-Label Trial of the Anti-HIV Activity of Delavirdine Mesylate (DLV; U-90,152S)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000808 | COMPLETED | PHASE1

49 participants

A Phase I Study of Safety and Pharmacokinetics of Nevirapine in HIV-1 Infected Pregnant Women and Neonates Born to HIV-1 Infected Mothers

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections
Pregnancy

Interventions

DRUG

No Results Yet

NCT00000803 | COMPLETED | PHASE2

471 participants

A Phase II Double-Blind Study of Delavirdine Mesylate ( U-90152 ) in Combination With Zidovudine ( AZT ) and/or Didanosine ( ddI ) Versus AZT and ddI Combination Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000802 | COMPLETED | PHASE3

700 participants

A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or Sulfonamides

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

Pneumonia, Pneumocystis Carinii
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000800 | COMPLETED | PHASE1

15 participants

Methadone Effects on Zidovudine (ZDV, AZT) Disposition

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000792 | COMPLETED | PHASE1

24 participants

A Pharmacologically Guided Phase I/II Study of Daily Orally Administered Synthetic Hypericin in HIV-Infected Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000790 | COMPLETED | PHASE2

164 participants

Thalidomide for Treatment of Oral and Esophageal Aphthous Ulcers and HIV Viremia in Patients With HIV Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections
Stomatitis, Aphthous

Interventions

DRUG

No Results Yet

NCT00000789 | COMPLETED | PHASE2

230 participants

A Randomized, Comparative Trial of Zidovudine (AZT) Versus 2',3'-Didehydro-3'-Deoxythymidine (Stavudine; d4T) in Children With HIV Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000782 | COMPLETED | PHASE1

50 participants

A Phase I/II Study of Delayed-Type Hypersensitivity (DTH) Reactions to Intradermal HIV Envelope Antigen

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000781 | COMPLETED | PHASE2

1292 participants

A Randomized, Double-Blind, Four-Arm Study Comparing Combination Nucleoside, Alternating Nucleoside, and Triple-Drug Therapy for the Treatment of Advanced HIV Disease (CD4 <= 50/mm3)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000779 | COMPLETED | PHASE1

130 participants

A Phase I Comparative Blinded Trial of Several HIV-1 Derived Immunogens in Infected Individuals With >= 500 CD4 Cells/mm3

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000774 | COMPLETED | PHASE1

156 participants

A Phase I Study to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Antigen in Children Born to HIV-Infected Mothers

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections
HIV Seronegativity

Interventions

BIOLOGICAL

No Results Yet

NCT00000771 | COMPLETED | PHASE2

68 participants

A Double-Blind, Placebo-Controlled Trial of Paromomycin for Treatment of Cryptosporidiosis in Patients With Advanced HIV Disease and CD4 Counts Under 150 Cells/mm3

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

Cryptosporidiosis
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000770 | COMPLETED | PHASE2

400 participants

A Comparative Study of a Combination of Zidovudine, Didanosine, and Double-Blinded Nevirapine Versus a Combination of Zidovudine and Didanosine

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000768 | COMPLETED | PHASE1

24 participants

A Randomized Comparative Pharmacokinetic Study of Oral Ganciclovir After Treatment With Intravenous Ganciclovir for Cytomegalovirus Gastrointestinal Disease in AIDS Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

Colitis
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000758 | COMPLETED | PHASE3

158 participants

A Phase III Randomized Trial of Topical Vaginal Fluorouracil (5-Fluorouracil, 5-FU) Maintenance Therapy Versus Observation After Standard Treatment for High-Grade Cervical Dysplasia in HIV-Infected Women

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections
Cervix, Dysplasia

Interventions

DRUG

No Results Yet

NCT00000757 | COMPLETED | PHASE1

30 participants

A Phase I Multicenter Trial to Evaluate the Safety and Immunogenicity of HIV-1 Recombinant Envelope Glycoprotein gp160

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000755 | COMPLETED | PHASE1

168 participants

A Phase I/II Trial of Vaccine Therapy of HIV-1 Infected Individuals With 50-500 CD4 Cells/mm3

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-04

Conditions

HIV Infections

Interventions

BIOLOGICAL
DRUG

No Results Yet