Clinical Trials

NCT01290354 | COMPLETED | PHASE1

10 participants

Exploratory Lapatinib (Positron Emission Tomography) PET Study in Subjects With Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2011-09-12

Completion:

2013-03-18

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT01265810 | COMPLETED | PHASE3

64 participants

Caphosol in Oral Mucositis Due to Targeted Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2011-11-30

Completion:

2015-08-31

Conditions

• Oral Complaints
• Renal Cell Carcinoma
• Hepatocellular Carcinoma
• Gastrointestinal Stromal Tumors

Interventions

• OTHER

No Results Yet

NCT01262963 | COMPLETED | PHASE1

4 participants

An Absorption, Distribution, Metabolism and Excretion (ADME) Study of Single Oral Dose [14C] GSK2118436 in Subjects With BRAF Mutant Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2011-01-26

Completion:

2011-04-08

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT01192165 | COMPLETED | PHASE1

169 participants

Safety and Tolerability Study of GSK1120212, a MEK Inhibitor, in Combination With Docetaxel, Erlotinib, Pemetrexed, Pemetrexed + Carboplatin, Pemetrexed + Cisplatin, or Nab-Paclitaxel

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2010-09-14

Completion:

2013-10-07

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT01141660 | COMPLETED | NA

131 participants

Use of Laryngeal Mask Airway in Pediatric Adenotonsillectomy

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2007-12-31

Completion:

2009-08-31

Conditions

• Laryngeal Mask Airway
• Tonsillectomy

Interventions

• DEVICE

Results Available

NCT01138085 | COMPLETED | PHASE1

240 participants

Safety, Pharmacokinetics (PK) of AKT and MEK Combination

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2010-05-04

Completion:

2014-11-19

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT01136005 | COMPLETED | PHASE3

160 participants

Bepanthen Versus Cetomacrogol in Epidermal Growth Factor Receptor Inhibitors (EGFRI)

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2010-09-30

Completion:

2016-12-31

Conditions

• Cancer
• Skin Rash

Interventions

• OTHER

No Results Yet

NCT01127919 | COMPLETED

3773 participants

Training Interventions and Genetics of Exercise Response (TIGER)

Study Type:

OBSERVATIONAL

Last Updated:

2017-11-13

Start Date:

2010-07-31

Completion:

2016-05-31

Conditions

• Exercise Response

Interventions

• BEHAVIORAL
• OTHER

No Results Yet

NCT01125072 | WITHDRAWN

0 participants

Use of Echocardiography in the Evaluation of Chest Pain in the Emergency Department

Study Type:

OBSERVATIONAL

Last Updated:

2017-11-13

Start Date:

2005-06-30

Completion:

2017-11-30

Conditions

• Chest Pain

Interventions

• OTHER

No Results Yet

NCT01110031 | COMPLETED | PHASE1

12 participants

Ofatumumab Cardiac Repolarization (QTc) Study in Fludarabine-Refractory Chronic Lymphocytic Leukemia Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2010-05-13

Completion:

2012-04-12

Conditions

• Leukaemia, Lymphocytic, Chronic

Interventions

• BIOLOGICAL

No Results Yet

NCT01092364 | COMPLETED | NA

365 participants

Cell Phone Intervention in Young Adults

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2010-11-30

Completion:

2014-10-31

Conditions

• Obesity

Interventions

• BEHAVIORAL

Results Available

NCT01075984 | COMPLETED | PHASE1

279 participants

Pharmacokinetics, Safety, and Tolerability of Intravenous Posaconazole Solution Followed by Oral Posaconazole Suspension in Subjects at High Risk for Invasive Fungal Infections (P05520)

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2010-02-23

Completion:

2012-11-20

Conditions

• Fungal Infection

Interventions

• DRUG

Results Available

NCT01066923 | COMPLETED | NA

124 participants

Enhanced Firefighter Rehab Trial: The Role of Aspirin in Preventing Heat Stress Induced Platelet Activation

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2010-02-28

Completion:

2011-06-30

Conditions

• Heat Stress Disorders

Interventions

• DRUG
• OTHER

Results Available

NCT01066000 | TERMINATED | PHASE4

33 participants

A Study for Monthly Methoxy Polyethylene Glycol-Epoetin Beta Treatment in Patients With Chronic Renal Anaemia

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-10-31

Completion:

2011-09-30

Conditions

• Anemia

Interventions

• DRUG

Results Available

NCT00996762 | COMPLETED | PHASE1

158 participants

A Study in Cancer Patients to Evaluate the Bioequivalence of Alternative Formulations of Lapatinib

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-11-12

Completion:

2012-09-18

Conditions

• Neoplasms, Breast

Interventions

• DRUG

No Results Yet

NCT00992121 | COMPLETED | PHASE1

11 participants

An Open-Label Pharmacodynamic Study of Bevacivumab and Pazopanib in Renal Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-11-18

Completion:

2013-11-01

Conditions

• Carcinoma, Renal Cell

Interventions

• DRUG

No Results Yet

NCT00959309 | COMPLETED | PHASE4

160 participants

Media Use in Preschooler Study (MUPS)

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2007-10-31

Completion:

2009-12-31

Conditions

• Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT00929500 | COMPLETED | NA

28 participants

Exercise Program in Women With Metabolic Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-07-31

Completion:

2010-05-31

Conditions

• Metabolic Syndrome

Interventions

• BEHAVIORAL

Results Available

NCT00920257 | COMPLETED | PHASE1

77 participants

A Phase I, Open-Label, First-Time-In-Human Study of the Oral AKT Inhibitor GSK2141795

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-06-16

Completion:

2013-04-17

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT00903422 | COMPLETED | PHASE1

98 participants

Eltrombopag Treatment of Thrombocytopenia in Subjects With Advanced Myelodysplastic Syndrome (MDS) or Secondary Acute Myeloid Leukemia After MDS (sAML/MDS)

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-05-14

Completion:

2012-06-26

Conditions

• Myelodysplastic Syndrome

Interventions

• DRUG
• OTHER

No Results Yet

NCT00880321 | COMPLETED | PHASE1

170 participants

A Phase I Study to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of GSK2118436 in Subjects With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-06-04

Completion:

2011-03-25

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT00866528 | COMPLETED | PHASE1

30 participants

Study of Pazopanib and Paclitaxel in Advanced Non-small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-07-09

Completion:

2012-10-25

Conditions

• Lung Cancer, Non-Small Cell

Interventions

• DRUG

No Results Yet

NCT00821054 | COMPLETED | PHASE1

24 participants

A Study to Examine the Effects of Low and High-fat Meals on Orally Administered Lapatinib in Metastatic ErbB2 Positive Breast Cancer Patients

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-03-06

Completion:

2011-03-22

Conditions

• Neoplasms, Breast

Interventions

• DRUG

No Results Yet

NCT00816556 | TERMINATED | PHASE3

63 participants

A Trial to Evaluate the Efficacy of Low Dose Vaginal Estrogens in the Treatment of Atrophic Vaginitis

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2008-10-31

Completion:

2011-09-30

Conditions

• Atrophic Vaginitis

Interventions

• DRUG

Results Available

NCT00815282 | COMPLETED | PHASE4

135 participants

Immune Response After Human Papillomavirus Vaccination in Patients With Autoimmune Disease

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-02-28

Completion:

2015-01-31

Conditions

• Juvenile Idiopathic Arthritis
• Systemic Lupus Erythematosus
• Juvenile Dermatomyositis

Interventions

• OTHER

No Results Yet

NCT00771810 | COMPLETED | PHASE2

34 participants

Study of Drug to Reduce Thrombocytopenia in Patients Receiving Chemo for Ovarian, Fallopian Tube or Peritoneal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2008-10-31

Completion:

2011-12-31

Conditions

• Thrombocytopenia
• Neutropenia
• Lymphopenia
• Anemia

Interventions

• DRUG

Results Available

NCT00755235 | COMPLETED | NA

208 participants

Feasibility of Depression Care Management by E-mail

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2009-04-30

Completion:

2010-04-30

Conditions

• Depression

Interventions

• OTHER

Results Available

NCT00732420 | COMPLETED | PHASE1

68 participants

Open-label Study of Topotecan and Pazopanib in Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2008-09-24

Completion:

2013-06-12

Conditions

• Solid Tumours

Interventions

• DRUG

No Results Yet

NCT00722293 | COMPLETED | PHASE1

111 participants

A Phase I, Open-label, Study of Pazopanib in Combination With Epirubicin or Doxorubicin for Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2008-07-08

Completion:

2012-06-11

Conditions

• Neoplasms, Breast

Interventions

• DRUG

No Results Yet

NCT00687622 | COMPLETED | PHASE1

206 participants

Open-label Study to Investigate the Safety, PK, and Pharmacodynamics of GSK1120212 in Subjects With Solid Tumors or Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2008-07-28

Completion:

2011-06-07

Conditions

• Solid Tumours

Interventions

• DRUG

No Results Yet

NCT00666978 | COMPLETED | PHASE4

540 participants

Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2007-12-31

Completion:

2010-06-30

Conditions

• Bladder Cancer
• Cervical Cancer
• Esophageal Cancer
• Gastric Cancer
• Head and Neck Cancer
• Kidney Cancer
• Leukemia
• Liver Cancer
• Lung Cancer
• Pancreatic Cancer
• Tobacco Use Disorder

Interventions

• BEHAVIORAL
• DRUG
• GENETIC
• OTHER
• PROCEDURE

Results Available

NCT00659555 | COMPLETED | PHASE1

24 participants

Study Of The Repeat Dosing Of Ketoconazole On The Pharmacokinetics Of A Single Dose Of Pazopanib (GW786034) Eye Drops

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2008-04-04

Completion:

2008-05-10

Conditions

• Macular Degeneration

Interventions

• DRUG

No Results Yet

NCT00598806 | COMPLETED | PHASE3

812 participants

Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-612)

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2007-08-31

Completion:

2012-01-31

Conditions

• Bladder Cancer

Interventions

• DRUG
• PROCEDURE

Results Available

NCT00570674 | TERMINATED | PHASE1/PHASE2

29 participants

Abraxane in Combination With Carboplatin, Erbitux and IMRT for Locally Advanced Squamous Cancer of the Head and Neck

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2007-11-30

Completion:

2013-10-31

Conditions

• Squamous Cell Carcinoma of the Head and Neck
• Basaloid Squamous Cell Carcinoma
• Undifferentiated Carcinoma
• Adenosquamous Cell Carcinoma

Interventions

• DRUG
• RADIATION

Results Available

NCT00519402 | WITHDRAWN

0 participants

Outcomes of Partial Versus Complete Tonsillectomy for Obstructive Sleep Disordered Breathing

Study Type:

OBSERVATIONAL

Last Updated:

2017-11-13

Conditions

• Obstructive Sleep Disordered Breathing

Interventions

• OTHER

No Results Yet

NCT00516672 | COMPLETED | PHASE1

30 participants

Phase I Study of Pazopanib Alone and In Combination With Lapatinib in Japanese Patients With Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2007-09-10

Completion:

2010-08-30

Conditions

• Carcinoma, Renal Cell

Interventions

• DRUG

No Results Yet

NCT00494364 | COMPLETED

28 participants

Gas Supply, Demand and Middle Ear Gas Balance: Specific Aim 3a Part ii

Study Type:

OBSERVATIONAL

Last Updated:

2017-11-13

Start Date:

2007-06-30

Completion:

2010-10-31

Conditions

• Healthy

No Results Yet

NCT00490568 | TERMINATED | PHASE3

1461 participants

Open-Label Extension Study Of Rosiglitazone XR As Adjunctive Therapy In Subjects With Mild-to-Moderate Alzheimers

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2007-08-08

Completion:

2009-06-01

Conditions

• Alzheimer's Disease

Interventions

• DRUG

Results Available

NCT00483860 | COMPLETED | PHASE1

59 participants

A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal Function

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2007-06-20

Completion:

2012-02-06

Conditions

• Solid Tumours

Interventions

• DRUG

No Results Yet

NCT00451321 | TERMINATED | PHASE2

88 participants

TRX4 Monoclonal Antibody in Type 1 Diabetes (T1 DM)

Study Type:

INTERVENTIONAL

Last Updated:

2017-11-13

Start Date:

2006-07-31

Completion:

2011-12-01

Conditions

• Diabetes Mellitus, Type 1

Interventions

• DRUG

Results Available