Open-label Study of Topotecan and Pazopanib in Advanced Solid Tumors
NCT00732420 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 68
Last updated 2017-11-13
Summary
To determined what dose of topotecan can be safely given with daily pazopanib.
Conditions
Interventions
- DRUG
-
topotecan
Topoisomerase I inhibition.
- DRUG
-
pazopanib
Tyrosine kinase inhibitor
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
GSK Clinical Trials · GlaxoSmithKline
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- SCREENING
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-09-24
- Primary Completion
- 2013-06-12
- Completion
- 2013-06-12
Countries
- United States
- Netherlands
Study Locations
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