Injectable Platelet-Rich Fibrin With Minimally Invasive Non-Surgical Technique in Treatment of Grade II Furcation Defects
NCT07787949 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2026-08-26
Summary
This study aims to compare the clinical and radiographic effectiveness of injectable platelet-rich fibrin (i-PRF) combined with minimally invasive non-surgical therapy (MINST) versus MINST alone in the management of class II furcation defects.
Conditions
- Injectable Platelet-Rich Fibrin
- Minimally Invasive
- Non-Surgical Technique
- Grade II Furcation Defects
Interventions
- PROCEDURE
-
Minimally invasive non-surgical technique (MINST)
Patients will receive minimally invasive non-surgical technique (MINST) alone
- PROCEDURE
-
Minimally invasive non-surgical technique (MINST) + injectable platelet-rich fibrin (i-PRF) injection
Patients will receive minimally invasive non-surgical technique (MINST) + injectable platelet-rich fibrin (i-PRF) injection
Sponsors & Collaborators
-
October 6 University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-03-11
- Primary Completion
- 2027-03-11
- Completion
- 2027-03-11
Countries
- Egypt
Study Locations
More Related Trials
-
Use of Injectable Extended Platelet-Rich Fibrin as a Local Drug Delivery in the Treatment of Stage II Periodontitis Patients
NCT07080294 ·Status: COMPLETED ·Phase: NA
-
Use of Platelet Rich Fibrin in Addition to CAF and SCTG for Treatment of Gingival Recession
NCT03199118 ·Status: COMPLETED ·Phase: NA
-
Comparative Evaluation of the Regenerative Capacity of Two Platelet Concentrates
NCT03698188 ·Status: UNKNOWN ·Phase: NA
-
Effectiveness of E-prf Alone and in Combination With Bioactive Glass Nanoparticles in Grade II Furcation Defects
NCT07042204 ·Status: COMPLETED ·Phase: NA
-
Platelet Rich Fibrin+1.2% Atorvastatin in Treatment of Mandibular Degree II Furcation Defects
NCT02612792 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Effect of I-PRF After Gingivectomy
NCT07174934 ·Status: COMPLETED ·Phase: NA
-
Treatment of Intrabony Defect in Patient With Periodontitis Stage III by Using I-PRF and Xenograft
NCT07261878 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects
NCT05730153 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.
NCT03695549 ·Status: UNKNOWN ·Phase: NA
-
Treatment of Mandibular Class II Furcation With Different Types of Biomaterials in Humans
NCT07738705 ·Status: COMPLETED ·Phase: NA
-
Clinical Evaluation of Injectable Alb-PRF in the Management of Intrabony Defect in Stage-III Periodontitis Patients
NCT06297577 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
PRF+1% MF for Class II Mandibular Furcation Defects
NCT03207698 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Extended Platelet- Rich Fibrin Membrane Combined With Vestibular Incision Subperiosteal Tunnel Access Technique to Treat Localized Gingival Recession
NCT07079293 ·Status: COMPLETED ·Phase: NA
-
Comparison of Two Different Types of Platelet Concentrate to Augment Bone Around Immediate Dental Implant
NCT05595772 ·Status: COMPLETED ·Phase: NA
-
Evaluation of The Effect of Injectable Platelet-rich Fibrin With Collagen Membrane in Miller Class II Gingival Recession Coverage
NCT07717398 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Different Scaffolds in Regenerative Endodontic Treatment
NCT06945965 ·Status: COMPLETED ·Phase: NA
-
Effect of Injectable Platelet-rich Fibrin on the En Masse Retraction of Maxillary Anterior Teeth
NCT05608356 ·Status: UNKNOWN ·Phase: NA
-
Injectable Platelet-Rich Fibrin and Microneedling For Papillae Reconstruction In Esthetic Zone
NCT06021301 ·Status: RECRUITING ·Phase: PHASE2
-
Injectable Platelet Rich Fibrin With Demineralized Freeze-dried Bone Allograft in Treatment of Intraosseous Defects
NCT03900013 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Advanced PRF Combined With Nano-crystalline Hydroxyapatite for Management of Grade II Furcation Defects
NCT03804086 ·Status: UNKNOWN ·Phase: NA
-
Efficacy of Combined Blood Clot and Platelet Rich Fibrin Scaffolds in Regeneration of Necrotic Immature Permanent Teeth
NCT04390854 ·Status: COMPLETED ·Phase: PHASE2
-
Comparison Between Two Regenerative Scaffolds
NCT06227533 ·Status: COMPLETED ·Phase: NA
-
Furcation Treatment With L-PRF and aPDT
NCT04842188 ·Status: COMPLETED ·Phase: NA
-
Comparing Microneedling and Injectable Platelet Rich Fibrin to Hyaluronic Acid In Papilla Reconstruction
NCT07280507 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Treated Dentine Matrix and Platelet Rich Fibrin in Induction of Root Formation of Non-Vital Immature Permanent Teeth
NCT05775081 ·Status: COMPLETED ·Phase: NA