Minimally Invasive Non Surgical Treatment Using Injectable Platelet Concentrate in Treatment of Deep Pockets.
NCT07722390 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2026-07-29
Summary
The purpose of this study is to evaluate change in pocket depth following using minimally invasive non surgical combined with injectable platelet concentrate .
Conditions
- Intrabony Periodontal Defects
Interventions
- BIOLOGICAL
-
Injectable PRF
I-PRF will be prepared from 10 mL of autologous venous blood and injected into the cleaned defect, followed by placement of a custom-made transparent vacuum-formed stent for 15 minutes to prolong local contact
- PROCEDURE
-
MINST
Participants will receive minimally invasive non-surgical periodontal therapy (MINST) alone using P3 Woodpecker piezoelectric scaler for the selected periodontal intrabony defect
Sponsors & Collaborators
-
Cairo University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-05-14
- Primary Completion
- 2027-12-31
- Completion
- 2028-06-30
Countries
- Egypt
Study Locations
More Related Trials
-
The Effect of A-PRF+ Versus Open Flap Debridement in the Treatment of Patients With Stage III Periodontitis
NCT03924336 ·Status: COMPLETED ·Phase: NA
-
The Use of Leucocyte Platelet Rich Fibrin (L- PRF) Covered Perforated Guided Tissue Membrane for Treatment of Periodontal Intrabony Defects
NCT04576468 ·Status: COMPLETED ·Phase: NA
-
Treatment of Intrabony Defects With L-PRF Membrane With or Without Collagen Membranes
NCT05496608 ·Status: COMPLETED ·Phase: NA
-
Injectable Platelet Rich Fibrin With Demineralized Freeze-dried Bone Allograft in Treatment of Intraosseous Defects
NCT03900013 ·Status: UNKNOWN ·Phase: NA
-
Use of Injectable Extended Platelet-Rich Fibrin as a Local Drug Delivery in the Treatment of Stage II Periodontitis Patients
NCT07080294 ·Status: COMPLETED ·Phase: NA
-
Efficacy of Injectable Platelet-rich Fibrin Versus Platelet-Rich Plasma As Adjunctive to Scaling and Root Planning in Non-surgical Periodontal Therapy of Periodontitis Patients
NCT06685393 ·Status: COMPLETED ·Phase: NA
-
Treatment of Intrabony Defect in Patient With Periodontitis Stage III by Using I-PRF and Xenograft
NCT07261878 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Concentrated Growth Factors in Treatment of Intrabony Defects in Localized Aggressive Periodontitis
NCT05001919 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Evaluation of Healing of Intra-bony Defects in Modified Minimal Invasive Surgical Technique
NCT03562039 ·Status: COMPLETED ·Phase: NA
-
Evaluation of iPRF With Vit.D As an Adjunct to Non-Surgical Therapy in the Treatment of Stage III Periodontitis
NCT06570200 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Effect of I-PRF After Gingivectomy
NCT07174934 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects
NCT05730153 ·Status: COMPLETED ·Phase: PHASE4
-
Clinical Evaluation of Injectable Alb-PRF in the Management of Intrabony Defect in Stage-III Periodontitis Patients
NCT06297577 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Evaluation of the Effect of Incorporation of Vitamin C Into Platelet Rich Fibrin Scaffold in Treatment of Intra-osseous Periodontal Defects
NCT03707483 ·Status: UNKNOWN ·Phase: PHASE2
-
Comparing the Position of Collagen Membrane During Immediate Implant Placement
NCT04224935 ·Status: COMPLETED ·Phase: NA
-
Clinical Evaluation of Nano-Hydroxyapatite as an Adjunctive to Minimally Invasive Non-Surgical Technique in the Treatment of Deep Intra-bony Defects
NCT07608783 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Growth Factors Release of PRF and PRGF
NCT02447510 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical Effect of APRF With DFDBA Compare to Collagen Membrane With DFDBA in Intraosseous Defect
NCT03922503 ·Status: UNKNOWN ·Phase: NA
-
Advanced Platelet Rich Fibrin in Periodontal Angular Defects
NCT03433066 ·Status: UNKNOWN ·Phase: NA
-
Microneedling With Platelet Rich Plasma Versus Microneedling Alone For Gingival Depigmentation
NCT07359339 ·Status: RECRUITING ·Phase: NA
-
The Present Study Was Performed to Evaluate the Efficacy of Lyophilized-PRF in Treatment of Periodontal Intra-bony Defects
NCT06625528 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Evaluation of Modified Minimally Invasive Surgical Technique and Platelet Rich Fibrin With or Without Vitamin Pool A and C for Management of Periodontal Intrabony Defects
NCT05499598 ·Status: COMPLETED ·Phase: NA
-
Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts
NCT07146776 ·Status: RECRUITING ·Phase: NA
-
Clinical and Radiograhic Evaluation of NIPSA With and Without Allograft Plus Platelet Rich Fibrin in the Treatment of Intraosseous Defects in Stage III Periodontitis Patients
NCT04444063 ·Status: COMPLETED ·Phase: NA
-
Evaluation of Platelet-rich Fibrin for Revascularization of Immature Permanent Teeth Versus Standard Apexification
NCT06693349 ·Status: COMPLETED ·Phase: PHASE3