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Effectiveness of E-prf Alone and in Combination With Bioactive Glass Nanoparticles in Grade II Furcation Defects

NCT07042204 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-01-13

No results posted yet for this study

Summary

The aim of the study is to evaluate and compare the effectiveness of extended platelet-rich fibrin (ePRF) alone and in combination with bioactive glass nanoparticles in the treatment of grade II furcation defects clinically and radiographically.

Conditions

  • Furcation Defects

Interventions

PROCEDURE

Group I (extended platelet-rich fibrin)

mucoperiosteal flap will be raised through sulcular incisions Debridement of granulation tissue from the osseous defect and furcation will be filled with (ePRF) at the first group

PROCEDURE

Group II (bioactive glass nanoparticles mixed with extended platelet-rich fibrin)

bioactive glass nanoparticles mixed with extended platelet-rich fibrin (BGn+ePRF)

PROCEDURE

Group III (bioactive glass nanoparticles and covered by a collagen membrane)

bioactive glass nanoparticles and covered by a collagen membrane

Sponsors & Collaborators

  • Merna Nasser Mohamed Mostafa Ibrahim Elnahas

    lead OTHER

Principal Investigators

  • Merna N Elnahas, Master's degree · Mansoura Unniversity

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-01-03
Primary Completion
2025-06-03
Completion
2025-08-03

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07042204 on ClinicalTrials.gov