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Benefits of Platelet Rich Fibrin In Mandibular Molar Furcation Defects

NCT02430519 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2017-04-07

No results posted yet for this study

Summary

Background: Furcation is the bifurcation or trifurcation of a multirooted tooth. It is an area of complex anatomic morphology difficult to debride by routine periodontal instrumentation. Multiple approaches have been used in an effort to treat the furcation Choukroun's platelet-rich fibrin (PRF), a second generation platelet concentrate has biochemical components which have well known synergetic effects on healing processes. The present study was conducted to evaluate the effectiveness of autologous platelet-rich fibrin (PRF) in the treatment of mandibular molar Grade 2 furcation defects in comparison to allograft and guided tissue regeneration (GTR) membrane.

Conditions

  • Chronic Periodontitis

Interventions

PROCEDURE

Furcation treatment with PRF

PRF Placed into the furcation after flap elevation and debridement

PROCEDURE

Furcation Treatment with Allograft and GTR

Allograft and GTR placed into furcation after flap elevation and debridement

DEVICE

allograft and guided tissue regeneration (GTR) membrane (DFDBM and Healiguide)

DEVICE

autologous platelet-rich fibrin

Sponsors & Collaborators

  • Dr.Syed Asimuddin

    lead OTHER

Principal Investigators

  • Rekha R Koduganti, MDS(Perio) · Prof & HOD,Dept of Periodontics,Panineeya Institute of dental sciences

  • Syed Asimuddin, MDS(Perio) · PG Student,Panineeya Institute of Dental Sciences

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-09-30
Primary Completion
2013-05-31
Completion
2013-05-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02430519 on ClinicalTrials.gov