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Salivary Gasdermin E and Granzyme B Levels in Patients With Periodontitis

NCT07755228 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 46

Last updated 2026-08-10

No results posted yet for this study

Summary

This observational study aims to compare salivary Gasdermin E and Granzyme B levels between individuals with periodontitis and periodontally healthy individuals. It will also evaluate the relationships between these biomarkers and clinical periodontal measurements. Saliva samples and periodontal clinical measurements will be collected from all participants. No treatment or experimental intervention will be administered as part of the study. The findings may contribute to a better understanding of the inflammatory mechanisms associated with periodontitis.

Conditions

  • Periodontitis
  • Periodontal Health

Sponsors & Collaborators

  • Medipol University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-06-11
Primary Completion
2026-08-04
Completion
2026-08-04

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07755228 on ClinicalTrials.gov