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Role of Craving in the Transition Across Level of Addiction Severity: A Longitudinal Study.

NCT07734363 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 700

Last updated 2026-07-29

No results posted yet for this study

Summary

Substance/Alcohol Use disorders are defined as a loss of control over the use despite harmul consequences, as well as an intense and persistent urge to use, also called craving. Previous research has shown that craving is central among the diagnostic criteria for addiction, suggesting that it may be important in the onset and persistence of addiction.

Addiction develops progressively, and it appears crucial to identify predictive markers of the transition from one level of severity to another over time. One hypothesis is that more closely linked symptoms (meaning symptoms that influence each other more) could be associated with greater severity and/or with the evolution of addiction severity over time.

The aim of this project is to explore how the characteristics of the association between addiction symptoms (diagnostic criteria and symptoms as they occur in daily life), and the importance of craving relative to other symptoms, could serve as markers of different addiction severities and of the transition across these levels of severity.

Conditions

Interventions

OTHER

Observational assessments (EMA and annual DSM-5 evaluations)

Participants are observed over two years. Annual DSM-5 diagnostic criteria for substance use disorders (SUD) are assessed, and participants complete 2-week EMA protocols measuring substance use, craving, and related factors four times per day. No intervention is administered.

Sponsors & Collaborators

  • Hospices Civils de Lyon

    collaborator OTHER

  • University of Bordeaux

    lead OTHER

Principal Investigators

  • Fuschia SERRE · University of Bordeaux

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-20
Primary Completion
2030-12-31
Completion
2031-06-30

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07734363 on ClinicalTrials.gov