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Learning in Young Adults as Predictor for the Development of Alcohol Use Disorders

NCT01744834 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 201

Last updated 2022-04-07

No results posted yet for this study

Summary

Overall goal of this study is to scrutinize the relation of learning behavior and related brain activity to the development of alcohol use disorder (AUD).

The researchers aim is to characterise a representative sample (200 men at age 18) with regard to learning parameters and their respective neural correlates which are thought to be indicators for the risk to develop an alcohol use disorder.

As part of a large multi-center study on alcohol dependency (in Dresden \& Berlin, Germany) the researchers will characterize the sample and then prospectively assess alcohol consumption and development of AUDs over a period of three years plus additional follow-ups after that period, depending on future funding.

Among other hypotheses it is expected that increased activation of striatal and prefrontal brain regions by the Pavlovian-to-instrumental transfer process is related to increased risk of developing an AUD.

Conditions

  • High-risk Alcohol Consumption Pattern
  • Low-risk Alcohol Consumption Pattern

Sponsors & Collaborators

  • Charite University, Berlin, Germany

    collaborator OTHER

  • Technische Universität Dresden

    lead OTHER

Principal Investigators

  • Michael Smolka, Prof MD · Technische Universität Dresden, Dresden, Germany

  • Andreas Heinz, Prof MD · Charité University, Berlin, Germany

  • Andreas Heinz, Prof MD · Charité University, Berlin, Germany

  • Hans-Ulrich Wittchen, Prof PhD · Technische Universität Dresden, Dresden, Germany

Eligibility

Min Age
18 Years
Max Age
18 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-12-31
Primary Completion
2018-04-30
Completion
2020-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01744834 on ClinicalTrials.gov