MedTrace Logo

The Effect of Olive Leaf Extract Supplementation on Training-induced Skeletal Muscle Functional and Molecular Adaptations in Healthy Volunteers

NCT07729072 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2026-07-27

No results posted yet for this study

Summary

The goal of this study is to investigate the effect of combining olive leaf extract supplementation with endurance training (moderate intensity continuous training or sprint interval training). We hypothesize that OLE supplementation during training, as compared to training alone with placebo, will translate into better performance outcomes. More specifically, we hypothesize that the additional benefits of OLE supplementation on performance will be mediated by improved mitochondrial characteristics in skeletal muscle and increased neural activation.

Conditions

  • Healthy Adult Participants
  • Exercise Training
  • Neuromuscular Adaptations
  • Nutritional Intervention

Interventions

DIETARY_SUPPLEMENT

Olive leaf extract

A capsule containing 250 mg of an olive leaf extract preparation will be swallowed with a glass of water daily for 21 days.

DIETARY_SUPPLEMENT

Placebo

A capsule containing 336 mg of cellulose microcrystalline will be swallowed with a glass of water daily for 21 days.

Sponsors & Collaborators

  • University of Lausanne

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-09-01
Primary Completion
2028-12-31
Completion
2029-12-31

Countries

  • Switzerland

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07729072 on ClinicalTrials.gov