MedTrace Logo

Radiation Therapy and Thymus Function in Young Women With Breast Cancer

NCT07725172 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 125

Last updated 2026-07-24

No results posted yet for this study

Summary

Breast cancer treatment sometimes includes radiation to the breast or chest wall. There is a small gland, called the thymus, located in the upper chest that may receive a small amount of the radiation aimed at the breast. The goal of this study is to collect blood samples from young women with breast cancer to study the effect of radiation therapy on the thymus gland.

Conditions

Interventions

PROCEDURE

Blood draw for the laboratory assessment

Blood will be drawn and processed for Peripheral Blood Mononuclear Cells (PBMCs). PBMC biomarkers will be used to assess thymopoiesis .

Sponsors & Collaborators

Principal Investigators

  • Susan McDuff, MD PhD · Duke University Health System (DUHS)

  • Andrew Macintyre, PhD · Duke Human Vaccine Institute

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-30
Primary Completion
2029-09-30
Completion
2029-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07725172 on ClinicalTrials.gov