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Modality-Specific Heart Rate Differences at Ventilatory Thresholds During Unified Ramp Testing

NCT07718594 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2026-07-22

No results posted yet for this study

Summary

The purpose of this study was to investigate the heart rate bias between cycling and treadmill exercise at ventilatory thresholds. This was a randomized crossover trial involving 23 healthy participants. Each participant performed both cycling and treadmill exercise tests in a randomized order. The primary outcome was to determine the difference in heart rate response at the first and second ventilatory thresholds between the two exercise modalities. We hypothesized that there is a fixed bias in heart rate response, which may have implications for exercise prescription in clinical and rehabilitation settings.

Conditions

  • Exercise Physiology
  • Ventilatory Threshold
  • Heart Rate
  • Cycling and Treadmill Exercise
  • Exercise (EX)

Interventions

DEVICE

Cycle Ergometer CPET

Following a 3-minute unloaded warm-up (0 W), continuous ramp increases began at 20 W/min for men or 15 W/min for women, targeting an 8-12 minute test duration to volitional exhaustion.

DEVICE

Motorized Treadmill CPET (Porszász Protocol)

Standardized ramp testing utilizing the Porszász algorithm. Simultaneous adjustments to speed and grade mathematically produce a linear rise in metabolic demand (matched to 20 or 15 W/min based on sex), ensuring identical oxygen uptake kinetic demands to the cycling protocol.

Sponsors & Collaborators

  • Cathay General Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-02-01
Primary Completion
2024-11-30
Completion
2024-11-30

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07718594 on ClinicalTrials.gov