Home Play-based Intervention for Parents and Infants

Summary

The goal of this clinical trial is to learn whether a 12-week home-based intervention (Sociometric Play-based Remediation of Individual Neurodevelopmental Trajectories (SPRINT)) helps support parenting and the development of infants aged 7 - 15 months (at the time they join the study) who were born preterm and/or have a higher family risk of developmental conditions, such as autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and/or global developmental delay (GDD). The main questions it aims to answer are:

* Does taking part in the SPRINT intervention help parents develop parenting skills?
* Does taking part in the SPRINT intervention improve infant's thinking skills and/or socio-emotional development?

Researchers will compare families who receive the SPRINT intervention with families in a waitlist control group to see whether the intervention leads to greater improvements in parents and their children.

Participants will:

* Complete questionnaires and in-person assessments, before and after the 12-week period.
* Be assigned to either the SPRINT intervention or a waitlist control group and complete the assigned activities for 12 weeks.
* Use the SPRINT app, which provides information, guidance and activities for either the SPRINT intervention or waitlist control group.

Conditions

• Attention-Deficit/Hyperactivity Disorder (ADHD)
• Autism Spectrum Disorder
• Premature Birth
• Global Developmental Delay

Interventions

BEHAVIORAL

SPRINT Intervention

The SPRINT intervention is a 12-week, home-based, parent-delivered programme designed to promote responsive caregiving, parental and child executive function, emotion regulation, and child's socio-emotional development. The intervention is delivered via the SPRINT app and comprises six concurrent modules: (A) Awareness, (B) Bond, (C) Cognition, (D) Decode, (E) Emotions, and (F) Fun. On average, participants are expected to engage with programme activities for approximately 25 minutes per day. Automated reminders are provided to support adherence, and participant engagement and responses are monitored throughout the intervention. During the intervention period, home visits will also be conducted to provide study devices, programme orientation, training, and technical support. Brief parent-child play interaction recordings collected during these visits may also be used for analysis and to facilitate module content.

OTHER

Waitlist Protocol

Participants will complete brief app-based activities during the 12-week waitlist period using the study devices provided. These activities are designed to maintain participant engagement without providing structured training targeting cognitive or socio-emotional skills, and involve simple visual or sensory interactions (e.g., tapping tasks or basic touch-based activities). The app will also send reminders, and activity completion will be logged.

Sponsors & Collaborators

• Agency for Science, Technology and Research (A*STAR)

  collaborator OTHER_GOV

• KK Women's and Children's Hospital

  collaborator OTHER_GOV

• Institute for Human Development and Potential (IHDP), Singapore

  collaborator OTHER

• Nanyang Technological University

  lead OTHER

Study Design

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

9 Months

Max Age

15 Months

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2026-07-31

Primary Completion

2029-03-31

Completion

2030-03-31

Countries

• Singapore

Study Locations