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Different Treatment Options For Mature Teeth With Apical Periodontitis

NCT07700394 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-07-15

No results posted yet for this study

Summary

A randomized control trial which aim to compare the healing potential for the following treatment options for mature teeth with apical periodontitis:

Group I: Conventional root canal treatment (CRT) Group II: Regenerative endodontic treatment (RET) using a blood clot scaffold Group III: RET using a blood clot scaffold loaded with recombinant human BMPs (rhBMPs)

Conditions

  • Apical Periodontitis

Interventions

PROCEDURE

root canal treatment and intracanal medicament

conventional root canal treatment with obturation

PROCEDURE

Regeneration

Regeneration using induction of bleeding

PROCEDURE

Regeneration with BMPs

RET using a blood clot scaffold loaded with recombinant human BMPs (rhBMPs)

Sponsors & Collaborators

  • Sara Tariq Elemam

    lead OTHER

Principal Investigators

  • Shehab El Din Mohamed Saber, PHD · Faculty of dentistry Ain Shams University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-12-01
Primary Completion
2026-04-01
Completion
2026-04-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07700394 on ClinicalTrials.gov