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Effect of Bio-C Temp Versus Calcium Ydroxide as Intracanal Dressings on Postoperative Pain Intensity and Periapical MMP-9 Level in Patients With Necrotic Pulp

NCT07101029 · Status: NOT_YET_RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-08-03

No results posted yet for this study

Summary

To compare the effect of Bio-C Temp Bioceramic intracanal dressing versus calcium hydroxide as intracanal medicaments on:

* Intensity of postoperative pain
* levels of MMP -9 in Periapical Fluids.

Conditions

  • Intracanal Dressing
  • Apical Periodontitis
  • Calcium Hydroxide
  • Biomarkers
  • Inflammatory Mediators

Interventions

DRUG

Bio-C Temp Intracanal Medication

Bio-C Temp Bioceramic intracanal dressing in the form of injectable premixed paste

DRUG

Calcium Hydroxide Intracanal medication

Calcium Hydroxide intracanal dressing in the form of injectable premixed paste

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-31
Primary Completion
2026-07-31
Completion
2026-07-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07101029 on ClinicalTrials.gov