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The Impact of Using Different Final Irrigation Modes on Postoperative Pain Following Root Canal Treatment of Non-vital Mandibular First Molar With Periapical Lesion.

NCT07623629 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2026-06-03

No results posted yet for this study

Summary

The goal of this clinical trial is to learn which rinsing of root canals method works best to lower pain after a root canal in adults. The study focuses on participants aged 20 to 40 with an infection in a lower back tooth (mandibular first molar) and a small area of bone loss at the root tip.

The main questions it aims to answer are:

Does the type of tool used to rinse the tooth root canal change how much pain a participant feels after treatment?

Does the cleaning method lower the number of painkillers a participant needs to take?

Researchers will compare four different rinsing tools-ranging from a standard needle to advanced vacuum and vibration devices-to see if using suction and sound waves can lower pain levels.

Participants will:

Receive a complete root canal treatment in a single visit

Be randomly assigned to one of four cleaning groups (standard rinse, vibration, vacuum, or a combination of both)

Rate their pain on a scale of 0 to 10 at five specific times: before the visit, and at 6, 12, 24, and 48 hours after treatment

Record how many painkiller tablets (Ibuprofen) they take during the two days following the procedure

Conditions

  • Necrotic Pulp With Symptomatic Apical Periodontitis

Interventions

PROCEDURE

root canal treatment

single visit root canal treatment with final irrigation protocol according to arm

Sponsors & Collaborators

  • Future University in Egypt

    lead OTHER

Principal Investigators

  • hesham mohamed salah, lecturer · Future University in Egypt

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-01-03
Primary Completion
2026-05-05
Completion
2026-10-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07623629 on ClinicalTrials.gov