External Validation of AI-Aided Weaning Software Using Multicenter Retrospective Data
NCT07658131 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1500
Last updated 2026-06-22
Summary
This multicenter retrospective study aims to externally validate an artificial intelligence-aided weaning software developed using intensive care unit data from Taichung Veterans General Hospital between 2015 and 2019. The model predicts the optimal timing for extubation using routinely collected clinical variables including ventilator parameters, physiologic measurements, and fluid and nutrition information. De-identified data from four hospitals collected between 2020 and 2024 will be used to evaluate model performance. Performance metrics include sensitivity, specificity, accuracy, area under the receiver operating characteristic curve (AUROC), and F1 score.
Conditions
- Respiratory Failure
- Mechanical Ventilation
- Critical Illness
Sponsors & Collaborators
-
Mackay Memorial Hospital
collaborator OTHER -
Kaohsiung Medical University Chung-Ho Memorial Hospital
collaborator OTHER -
Tungs' Taichung Metroharbor Hospital
collaborator UNKNOWN -
Taichung Veterans General Hospital
lead OTHER
Eligibility
- Min Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-01-01
- Primary Completion
- 2024-12-31
- Completion
- 2024-12-31
Countries
- Taiwan
Study Locations
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