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Ultrasound Muscle Biomarkers as Predictors of Isometric Quadriceps Muscle Strength and Handgrip in Healthy Adults: an Observational Study

NCT07647393 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2026-06-16

No results posted yet for this study

Summary

This observational study aims to determine whether ultrasound-derived muscle biomarkers can predict isometric quadriceps muscle strength and handgrip in healthy adults aged 18-89 years.

The main questions it aims to answer are:

* Which ultrasound muscle characteristics are associated with isometric quadriceps muscle strength and handgrip?
* Can ultrasound-derived biomarkers be used to develop predictive models of muscle strength in healthy adults?

Participants will undergo:

* Ultrasound assessment of the quadriceps and forearm flexor muscles;
* Measurement of isometric quadriceps muscle strength and handgrip using standardized dynamometry protocols;
* Assessment of functional capacity, mobility and balance;
* Completion of questionnaires related to health status, physical activity, nutrition, fatigue and health-related quality of life.

The study will also assess the reliability of ultrasound measurements and explore the relationship between ultrasound variables, muscle strength, physical function and health-related factors.

Conditions

  • Healthy Adult
  • Muscle Strength
  • Skeletal Muscle Ultrasound

Sponsors & Collaborators

  • University of Alcala

    lead OTHER

Principal Investigators

  • Nicola S. Diciolla, PT, Ph.D. · University of Alcalá

Eligibility

Min Age
18 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-06-30
Primary Completion
2028-06-30
Completion
2029-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07647393 on ClinicalTrials.gov