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Postoperative Pain and Substance P Levels After Bioceramic vs Calcium Hydroxide Intracanal Medicaments in Symptomatic Apical Periodontitis

NCT07585721 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2026-05-14

No results posted yet for this study

Summary

Clinical Evaluation of the Postoperative Pain and Substance P levels Following the use of Bioceramic verses Calcium Hydroxide Intracanal Medicaments in Permanent Mandibular molars with Symptomatic Apical Periodontitis

Conditions

  • Symptomatic Apical Periodontitis

Interventions

DRUG

Calcium Hydroxide (Ca(OH)2)

Calcium hydroxide will be used as an intracanal medicament during root canal treatment in Permanent Mandibular molars with Symptomatic Apical Periodontitis

DRUG

Bioceramic Intracanal Medicament

Bioceramic material will be used as an intracanal medicament during root canal treatment in Permanent Mandibular molars with Symptomatic Apical Periodontitis

Sponsors & Collaborators

  • Future University in Egypt

    lead OTHER

Principal Investigators

  • Adel Abdelwahed, Prof. Ass. of endodontic · Prof. Ass. of endodontic, faculty of Oral and Dental Medicine Future University in Egypt

  • Marwa Moataz abo shadi, Lecturer of Endodontics · Lecturer of Endodontics, Faculty of Oral and Dental Medicine, Future university in Egypt

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-06-01
Primary Completion
2027-02-01
Completion
2027-02-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07585721 on ClinicalTrials.gov