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Abdominal Midline Wound Closure: Small Tissue Bites Versus Large Tissue Bites

NCT07621926 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 88

Last updated 2026-06-02

No results posted yet for this study

Summary

The goal of this clinical trial is to learn whether a small stitch technique works better than a large bite technique for closing midline abdominal surgery wounds in adults having midline laparotomy surgery.

The main questions it aims to answer are:

Does the small stitch technique lower the risk of surgical site infection? Does the small stitch technique lower the risk of wound dehiscence (reopening of the wound)? Researchers will compare the small stitch technique with the large bite technique to see if the small stitch technique leads to fewer wound complications after surgery.

Participants will:

Have their abdominal wound closed using either the small stitch or large bite technique during surgery Attend follow-up visits at 2 weeks and 1 month after surgery Be checked for wound complications, including infection and wound reopening In the small stitch technique, stitches are placed 5 millimeters from the wound edge and 5 millimeters apart. In the large bite technique, stitches are placed 10 millimeters apart.

Conditions

  • Stitch Technique

Interventions

PROCEDURE

Small Stitch Closure Technique

In this technique, sutures are placed approximately 5 millimeters apart using a continuous suturing method.

PROCEDURE

Large Stitch Closure Technique

In this technique, sutures are placed approximately 10 millimeters apart using a continuous suturing method.

Sponsors & Collaborators

  • Indus Hospital and Health Network

    lead OTHER

Principal Investigators

  • Nazia Lodhi, MBBS, FCPS · Indus Hospital and Health Network

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-05-01
Primary Completion
2026-02-28
Completion
2026-03-30

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07621926 on ClinicalTrials.gov