MedTrace Logo

Evaluating the Relationship Between Function and Structure Using Data From a GA Natural History Cohort

NCT07424235 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2026-05-11

No results posted yet for this study

Summary

Geographic atrophy (GA) is an advanced form of dry age-related macular degeneration that leads to progressive and irreversible vision loss. The course of visual decline varies widely among patients, and it is not always clear which anatomical features of the retina are associated with faster loss of vision.

This retrospective observational study aims to describe the natural history of vision loss in patients with geographic atrophy who have characteristics similar to those enrolled in recent clinical trials. The study will analyze previously collected clinical and imaging data from patients followed during routine clinical care at a single center.

The main goal of the study is to evaluate the relationship between changes in visual function and retinal anatomical features, such as the size and location of atrophic lesions and retinal layer integrity, using fundus autofluorescence and optical coherence tomography images.

No treatments or study procedures are performed as part of this research. All data used in the study were collected during standard clinical practice and analyzed retrospectively.

Conditions

  • Age Related Macular Degeneration (AMD)
  • Age Related Macular Degeneration
  • AMD
  • Geographic Atrophy
  • Geographic Atrophy Secondary to Age-related Macular Degeneration
  • Geographic Atrophy (GA) Secondary to Dry Age-related Macular Degeneration (AMD)

Sponsors & Collaborators

  • IRCCS Ospedale San Raffaele

    lead OTHER

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-01-31
Primary Completion
2024-12-31
Completion
2024-12-31

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07424235 on ClinicalTrials.gov