Progression of Early Atrophic Lesions
NCT05959005 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 125
Last updated 2026-03-11
Summary
Early atrophic age-related macular degeneration (AMD) represents an important time window in the course of so far untreatable atrophic AMD, as patients typically experience only some degree of visual dysfunction, while being at significant risk for marked further loss of vision. To allow the precise evaluation of upcoming therapeutic interventions, a better understanding of the manifestation and variable disease progression is needed. This project aims to investigate refined tools to detect and monitor early atrophic AMD more accurately, including the impact on visual dysfunction and quality of life.
Conditions
- Age-Related Macular Degeneration
Interventions
- OTHER
-
No intervention
There is no intervention.
Sponsors & Collaborators
-
National Eye Institute (NEI)
collaborator NIH - lead OTHER
Principal Investigators
-
Monika Fleckenstein · University of Utah
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-10-20
- Primary Completion
- 2028-06-30
- Completion
- 2028-12-31
Countries
- United States
Study Locations
More Related Trials
-
Functional and Anatomical Visual Investigations in Patients With Early Forms of Age-related Macular Degeneration
NCT06694272 ·Status: RECRUITING
-
Evolution and Risk Factors Associated With Geographic Atrophy Progression
NCT01694095 ·Status: COMPLETED
-
Sparing of the Fovea in Geographic Atrophy Progression
NCT02332343 ·Status: COMPLETED
-
Timing of Low Vision Rehabilitation in Anti- Vascular Endothelial Growth Factor (VEGF) Therapy
NCT03065907 ·Status: COMPLETED ·Phase: NA
-
Visual Function Change in Wet Age-related Macular Degeneration Patients With Better Baseline Visual Acuity
NCT06330220 ·Status: COMPLETED ·Phase: PHASE4
-
Optical Coherence Tomography and Microperimetry Biomarker Evaluation in Patients With Geographic Atrophy Study
NCT05963646 ·Status: COMPLETED
-
A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)
NCT07144137 ·Status: RECRUITING
-
Active AMD Study to Improve Function in Veterans
NCT05932069 ·Status: RECRUITING ·Phase: NA
-
The Effect of Duration Between Sessions on Microperimetric Biofeedback Training in Patients With Maculopathies
NCT05904444 ·Status: COMPLETED ·Phase: NA
-
Retinal Imaging by Adaptive Optics in Healthy Eyes and During Retinal and General Diseases
NCT01546181 ·Status: COMPLETED
-
The Effect of Phacoemulsification on the Macular Changes in Patients with Neovascular Age-related Macular Degeneration
NCT06759597 ·Status: NOT_YET_RECRUITING
-
Therapy of Age-related Macular Degeneration
NCT05222997 ·Status: UNKNOWN
-
Retinal Therapy Guided by 3D OCT Image Analysis
NCT02308215 ·Status: COMPLETED
-
A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression
NCT05698316 ·Status: COMPLETED
-
Single In-Clinic Encounter With the Notal Vision Home OCT
NCT04642183 ·Status: COMPLETED
-
Telemedicine in Age-Related Macular Degeneration
NCT04863391 ·Status: UNKNOWN
-
Identification and Treatment of Feeder Vessels in Macular Degeneration
NCT00018070 ·Status: COMPLETED ·Phase: PHASE1
-
Personalized Monitoring of Non-foveal, Non-vision Compromising Atrophic Age-related Macular Degeneration With Artificial Intelligence and Identification of Disease Progression
NCT06351657 ·Status: RECRUITING
-
Age-Related Macular Degeneration (AMD) - Usability Study
NCT00963339 ·Status: COMPLETED
-
Comparison of Cytokine Profiles in Aqueous Humor of Patients With Age Related Macular Degeneration (AMD)
NCT03418220 ·Status: COMPLETED ·Phase: NA
-
Size Progression of Macular Degeneration After Cataract Surgery
NCT01165801 ·Status: COMPLETED ·Phase: PHASE4
-
Ocular, Vascular, and Genetic Findings in AMD Patients
NCT06015633 ·Status: ACTIVE_NOT_RECRUITING
-
Optical Coherence Tomography Angiography Criteria Of The Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia (Comparative Study).
NCT05562336 ·Status: UNKNOWN
-
Non-invasive Optical Angiography in Age-related Macular Degeneration
NCT02521142 ·Status: UNKNOWN
-
Vision Outcomes Using Quantitative Optical Coherence Tomography Evaluation in Age Related Macular Degeneration
NCT02422160 ·Status: COMPLETED