Safety of Perioperative Anticoagulation Management in People With Active Cancer Undergoing Cancer-Related Surgery or Procedures (ACE-HIGH Study)
NCT07372716 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 700
Last updated 2026-02-06
Summary
The purpose of this study is to help find how safe current practices are when managing blood thinners in people with cancer who are having surgery or medical procedures. Investigators will also measure how often bleeding or clotting problems happen in this setting. The goal is to use this information to improve future care and reduce these risks for patients. This study will determine whether contemporary practices can be safely applied to cancer patients, and also evaluate the blood thinner level left over in patient's body at the time of surgery.
Conditions
- Thrombosis
- Cancer
- Thrombosis, Deep Vein
- Atrial Fibrillation (AF)
- Venous Thromboembolic Event
- Bleeding
Interventions
- OTHER
-
standardized perioperative anticoagulation management Guideline
The intervention is implementing a standardized perioperative anticoagulation management strategy in patients with active cancer (and this strategy is consistent with guideline-directed care for patients with active cancer).
Sponsors & Collaborators
-
Ottawa Hospital Research Institute
lead OTHER
Principal Investigators
-
Joseph Shaw, MD, MSc, FRCPC · Ottawa Hospital Research Institute
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-03-31
- Primary Completion
- 2030-12-31
- Completion
- 2031-12-31
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