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Diet Synergy in Muscle Protein Synthesis

NCT07367854 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2026-05-01

No results posted yet for this study

Summary

In the present semi-crossover randomized design, 15 recreationally active young adults (19-40 y) will receive stable isotope tracer infusions and perform a single bout of resistance exercise. Immediately after exercise, participants will ingest either 1 medium russet potato with skins and 2 ounce-equivalent lean ground beef combination (274 kcals, 19.3 g protein, 5 g fat, 37 g carbohydrates, and 4 g fiber), 2 slices of white bread and beef combination (262 kcals, 19.8 g protein, 6.8 g fat, 28 g carbohydrates, and 1.8 g fiber) or 2 ounce-equivalent beef (93% lean meat/7% fat; 110 kcals, 14.8 g protein, and 5 g fat). Repeated blood and muscle biopsies will be collected to determine whole body leucine kinetics, amino acid concentrations, anabolic signaling and myofibrillar protein synthesis rates during the trials.

Conditions

  • Muscle Protein Synthetic Response to Protein
  • Muscle Protein Synthesis
  • Muscle Health
  • Protein Metabolism
  • Recreational Activities
  • Isotope Labeling

Interventions

BEHAVIORAL

Resistance Exercise

Participants will perform leg press and leg extension immediately prior to ingestion of either potato-beef combination, bread-beef combination, or beef alone.

DIETARY_SUPPLEMENT

Potato and Beef

Participants will ingest baked russet potato and cooked ground beef immediately after resistance exercise.

DIETARY_SUPPLEMENT

Bread and Beef

Participants will ingest white bread and cooked ground beef immediately after resistance exercise.

DIETARY_SUPPLEMENT

Beef

Participants will ingest cooked ground beef immediately after resistance exercise.

Sponsors & Collaborators

  • University of Illinois at Urbana-Champaign

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
19 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-03-01
Primary Completion
2027-10-31
Completion
2028-11-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07367854 on ClinicalTrials.gov