Complications and Antiplatelet and Anticoagulant Therapy in Vascular Surgery.

Summary

The goal of this retrospective clinical trial is to find out association antiplatelet and anticoagulant therapy with perioperative complications in non-cardiac vascular surgery in patients . The main questions it aims to answer are:

Does the use of antiplatelet agents and anticoagulants affect the development of complications in the perioperative period during operations on the main arteries? Does discontinuing antiplatelet and anticoagulant medications affect the development of perioperative complications in major artery surgeries?? Researchers will compare with patients who didn't use antiplatelets and anticoagulant drugs to see ift he incidence of complications comparable?

This is a retrospective study based on the analysis of medical records (case histories).

Conditions

• Thrombosis
• Bleeding
• Cerebral Hypoxia During and/or Resulting From A Procedure

Interventions

DRUG

Aspirin + rivaroxaban

Patients who take aspirin and rivaroxaban until the operation day

DRUG

Clopidogrel + Apixaban

Patients who take clopidogrel and apixaban until the operation day

DRUG

Clopidogrel + Rivaroxaban

Patients who take clopidogrel and rivaroxaban until the operation day

DRUG

Aspirin + Ticagrelor

Patients who take aspirin and ticagrelor until the operation day

DRUG

Aspirin + Apixaban

Patients who take aspirin and apixaban until the operation day

DRUG

Aspirin

Patients who take aspirin until the operation day

DRUG

Clopidogrel

Patients who take clopidogrel until the operation day

DRUG

Ticagrelor

Patients who take ticagrelor until the operation day

DRUG

Dabigatran

Patients who take dabigatran until the operation day

DRUG

Rivaroxaban

Patients who take rivaroxaban until the operation day

DRUG

Apixaban

Patients who take apixaban until the operation day

DRUG

Warfarin

Patients who take warfarin until the operation day

DRUG

aspirin + clopidogrel

Patients who take aspirin and clopidogrel until the operation day

Sponsors & Collaborators

• Petrovsky National Research Centre of Surgery

  lead OTHER

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-05-01

Primary Completion

2026-02-12

Completion

2026-02-28

Countries

• Russia

Study Locations