MedTrace Logo

Cold Plasma Effects on Dental Implant Stability

NCT07348770 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 11

Last updated 2026-05-11

No results posted yet for this study

Summary

Cold plasma-mediated implant surface activation may reverse the biological aging of titanium by enhancing hydrophilicity and cellular response. The aim of this study was to clinically compare the effects of three different cold plasma systems on the stability of dental implants. In this prospective randomized controlled within-patient trial, a total of 44 implants were placed in 11 patients. In each patient, four implants were randomly allocated to one of the following groups: control, vacuum plasma, argon jet plasma, and cold atmospheric plasma. All implants were placed using a single-stage protocol with a minimum insertion torque of 45 Ncm. Implant stability was assessed using resonance frequency analysis (ISQ values) immediately after placement and at 2, 4, and 8 weeks.

Conditions

  • Cold Atmospheric Plasma
  • Dental Implants

Interventions

PROCEDURE

Dental implant placement

The dental implant was placed without any plasma application.

PROCEDURE

Dental implant placement and vacuum plasma application

The dental implant was placed with non-thermal low-pressure cold plasma application

PROCEDURE

Dental implant placement and argon jet plasma application

The dental implant was placed with argon jet plasma application

PROCEDURE

Dental implant placement and cold atmospheric plasma application

The dental implant was placed with cold atmospheric plasma application

Sponsors & Collaborators

  • Kahramanmaras Sutcu Imam University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-24
Primary Completion
2025-07-08
Completion
2025-09-09

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07348770 on ClinicalTrials.gov