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Biomarker-guided Implementation of the AKI Bundle

NCT03244514 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 280

Last updated 2020-02-19

No results posted yet for this study

Summary

There is no specific therapy for acute kidney injury. It is presumed that supportive measures improve the care and outcome of patients with acute kidney injury.

The investigators hypothesize that the implementation of a bundle of supportive measures adapted to patients undergoing cardiovascular surgery reduces the occurence of AKI.

A Randomized prospective multicenter trial is needed to investigate whether the implementation of the bundle of measures is effective to prevent AKI in high risk patients undergoing cardiac surgery. In this feasibility trial the investigators will analyze the compliance rate to the trial protocol in a multicenter, multinational cohort in preparation for a large randomized controlled trial.

Conditions

  • Acute Kidney Injury (Nontraumatic)

Interventions

OTHER

Intervention

Implementation of the cardiovascular AKI bundle (see arm description)

Sponsors & Collaborators

  • European Society of Intensive Care Medicine

    collaborator OTHER

  • University Hospital Muenster

    lead OTHER

Principal Investigators

  • Zarbock, PhD · University Hospital Muenster, Dept. of Anesthesiology

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-11-02
Primary Completion
2019-10-26
Completion
2020-01-26

Countries

  • Belgium
  • Germany
  • Italy
  • Spain
  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03244514 on ClinicalTrials.gov