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Acute Kidney Injury After Cardiac Surgery

NCT05079724 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2021-10-19

No results posted yet for this study

Summary

The study aims to identify the Following: -

1. incidence and mortality of cardiac Surgery associated -AKI based on the new consensus diagnostic systems of KDIGO (Kidney Disease Improving Global Outcomes).
2. use of biomarkers for the early detection of clinical and subclinical cardiac Surgery associated-AKI.
3. risk factors and prediction models of cardiac Surgery associated-AKI.
4. optimal cardiac surgical procedures including conventional versus minimally invasive approaches, on-pump versus off-pump, and optimal management of cardiac surgical support including duration of CPB, perfusion pressure, hemodilution, and hypothermia during CPB.
5. controversial pharmacologic therapies for the prevention and treatment of cardiac Surgery associated-AKI including statins, sodium bicarbonate, and N-acetylcysteine (NAC).

Conditions

  • Heart Diseases
  • Heart Valve Diseases
  • Heart Shock
  • Cardiac Disease
  • Cardio-Renal Syndrome
  • Cardio Respiratory Arrest
  • Cardiopulmonary Disease
  • Cardiopulmonary Arrest With Successful Resuscitation
  • Cardio-pulmonary Bypass
  • Cardiothoracic Surgery
  • Acute Kidney Injury
  • Acute Kidney Injury Due to Circulatory Failure
  • Coronary Artery Bypass Surgery

Interventions

PROCEDURE

Cardiac Surgery

About 3.5-31.0% of Patients undergoing cardiac surgery Complains from Postoperative Acute renal injury (AKI) that is a severe complication increasing the risk factor for mortality about 8-folds, The occurrence of AKI in patients undergoing cardiac surgery raises the mortality rate from 0.4-4.4% to 1.3-22.3%; when those same patients require dialysis.

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Omar A Sadek, M.Sc. · Assiut University

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-11-01
Primary Completion
2024-10-01
Completion
2024-11-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05079724 on ClinicalTrials.gov