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Pilot Study Evaluating brainQuant's Ability to Detect Alterations in White Matter in Diffusion MRI, Indicative of Post-traumatic Lesions

NCT07302503 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2025-12-24

No results posted yet for this study

Summary

Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease described in boxing, but also in contact sports such as American football.

Soccer, due to repeated headers, could also be associated, albeit to a lesser degree, with the development of this type of pathology.

Indeed, it has been shown that playing soccer can be accompanied by cognitive impairments, and neurodegenerative brain abnormalities have been described in neuropathology studies of former professional soccer players. Subradiological brain abnormalities have been found in multimodal MRI in various sports. Similarly, a decrease in cognitive performance has been described.

The discovery of this type of anomaly in a population of professional footballers nearing the end of their careers could lead to:

* The implementation of appropriate monitoring for professional footballers through early detection of lesions via MRI and cognitive disorders
* The implementation of preventative measures for professional footballers, but also for amateur footballers from a very young age.

Conditions

  • Chronic Traumatic Encephalopathy

Sponsors & Collaborators

  • University Hospital, Strasbourg, France

    lead OTHER

Eligibility

Min Age
32 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-09-10
Primary Completion
2028-03-31
Completion
2028-03-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07302503 on ClinicalTrials.gov