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Post-Concussion Syndrome in Professional Athletes: A Multidisciplinary Study

NCT03218332 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2021-09-29

No results posted yet for this study

Summary

to examine the relationship between repeated concussions and late decline of brain function. In addition, all participants agreeing to participate in the study will be asked to will their brains to The Krembil Neuroscience Centre Concussion Project at the Toronto Western Hospital with the consent and full knowledge of their families and doctors. However, it is possible to participate in the research without agreeing to a brain donation.

The Project Team is specifically attempting a clinical-MRI-brain tissue research analysis to determine the exact mechanism of the damage to brain tissue following repeated concussions. This condition is known as chronic traumatic encephalopathy (CTE), and shows an abnormal protein in the brain called tau-protein.

Conditions

  • Chronic Traumatic Encephalopathy

Interventions

DIAGNOSTIC_TEST

Biomarkers for detecting possible CTE invivo

Detection biomarkers for possible CTE: Imaging/blood/CSF/PET-tau/MRI/europsychological assessment

Sponsors & Collaborators

  • The Weston A. Price Foundation

    collaborator OTHER

  • University Health Network, Toronto

    lead OTHER

Principal Investigators

  • Maria Carmela Tartaglia, M.D · Toronto Western Hopsital,UHN;Tanz CRND

  • Charles H Tator, M.D · Toronto Western Hopsital,UHN

Eligibility

Min Age
25 Years
Max Age
85 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-07-04
Primary Completion
2030-12-30
Completion
2030-12-30

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03218332 on ClinicalTrials.gov