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MEG and DTI of Neural Function and Connectivity in Traumatic Brain Injury

NCT01298557 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 69

Last updated 2018-12-04

No results posted yet for this study

Summary

The overall hypothesis is that the long-term cognitive and behavioral sequelae of traumatic brain injury (TBI) are due to selective disruption of the long association white matter tracts of the cerebral hemispheres, with resulting functional impairment of the network of cortical regions that are interconnected by these long-range association pathways. We propose that traumatic white matter injury can be measured with diffusion tensor imaging (DTI) and that the impaired cortical activation can be detected with magnetoencephalography (MEG), and that the results of these imaging examinations will correlate with neurocognitive status and functional recovery after TBI.

Conditions

Sponsors & Collaborators

Principal Investigators

  • Pratik Mukherjee, MD, PhD · UCSF Department of Radiology and Bioengineering

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-02-28
Primary Completion
2013-02-28
Completion
2013-02-28

Countries

  • United States

Study Locations

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Diseases
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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01298557 on ClinicalTrials.gov