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Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

NCT04124029 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 800

Last updated 2025-09-26

No results posted yet for this study

Summary

This is a research study that aims to examine whether Veterans with mild Traumatic Brain Injuries are at risk for dementia by studying their memory, brain wave activity, brain structure and proteins that can be elevated after brain injury and in dementia.

Conditions

Interventions

DEVICE

No Intervention is used for this study but all subjects will be asked to complete EEG testing and an MRI scan.

No intervention will be used.

PROCEDURE

No intervention is used for this study but all subjects will be asked to complete a venous blood draw procedure and a lumbar puncture procedure.

No intervention will be used.

Sponsors & Collaborators

  • VA Boston Healthcare System

    collaborator FED

  • VA Office of Research and Development

    lead FED

Principal Investigators

  • Katherine Turk, MD · VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

Eligibility

Min Age
30 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-07-01
Primary Completion
2026-06-30
Completion
2026-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04124029 on ClinicalTrials.gov