Effects of Dexmedetomidine Target Controlled Infusion on Patient State Index Values and Electroencephalographic Spectrum During Total Intravenous Anesthesia With Propofol
NCT07259460 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 60
Last updated 2025-12-23
Summary
Dexmedetomidine Target Controlled infusion (TCI, Dyck model) effects on Neuromonitoring during Total Intravenous Anesthesia (TIVA) with Propofol and Remifentanil TCI (Eleveld model) has not been investigate yet.
Authors aim to investigate its effect on Patient State index (PSi), the power spectrum EEG, the Analgesia Nociception Index (ANI) and pupillometry values during maintenance during TIVA-TCI with Propofol, Remifentanil and Dexmedetomidine.
Conditions
- Adjuvants, Anesthesia
Sponsors & Collaborators
-
University of Padova
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-12-01
- Primary Completion
- 2026-06-30
- Completion
- 2026-07-30
Countries
- Italy
Study Locations
More Related Trials
-
Influence of Dexmedetomidine on a Closed-Loop Anesthesia System
NCT00921284 ·Status: COMPLETED ·Phase: PHASE3
-
Dexmedetomidine Versus Propofol in Vitreoretinal Surgery
NCT01001429 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Hemodynamics Between Dexmedetomidine and Propofol for Sedation in Patients With Abdominal Surgery
NCT02393066 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Dexmedetomidine and Propofol on Regional Cerebral Tissue Oxygen Saturation
NCT03817112 ·Status: COMPLETED ·Phase: NA
-
EEG DSA-guided Intravenous Anesthesia Using Dexmedetomidine and Propofol
NCT05656547 ·Status: UNKNOWN
-
Effects of Dexmedetomidine on Cognitive Outcome and Brain Injury Markers
NCT03585452 ·Status: COMPLETED ·Phase: NA
-
Dexmedetomidine in Spinal Anesthesia
NCT02155010 ·Status: COMPLETED ·Phase: NA
-
Dexmeditomedine as an Adjuvant to Levobupivacaine in Transversus Thoracis Plane Block on the Management of Post-sternotomy Pain in Open-heart Surgeries
NCT06410404 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Study of Dexmedetomidine Pharmacokinetics for Preoperative Sedation
NCT03800641 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine for the Control of Post-Operative Pain in Thoracotomy Patients
NCT00345384 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Subtenon and Intravenous Dexmedetomidine Effect on Patients Undergoing Cataract Surgery
NCT04668456 ·Status: UNKNOWN ·Phase: PHASE3
-
Dexmedetomidine-propofol-remifentanil Anaesthesia and Reactivity to Noxious Stimuli
NCT01076790 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Dexmedetomidine Upon Sleep Postoperatively
NCT00333632 ·Status: WITHDRAWN ·Phase: PHASE4
-
Dexmedetomidine in IVRA
NCT05123170 ·Status: COMPLETED ·Phase: PHASE4
-
Cognitive Functions After TIVA With Dexmedetomidine
NCT02631135 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperative Period
NCT04577430 ·Status: COMPLETED ·Phase: NA
-
Intrathecal Versus Intravenous Dexmeditomedine in Transurethral Resection of the Prostate
NCT04618965 ·Status: UNKNOWN ·Phase: PHASE4
-
A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation
NCT03255824 ·Status: COMPLETED ·Phase: PHASE4
-
Cerebral Vascular Effects of Dexmedetomidine Versus Propofol Sedation in Intubated Mechanically Ventilated ICU Patients
NCT03285165 ·Status: SUSPENDED ·Phase: PHASE2/PHASE3
-
Morphine, Midazolam and Dexmedetomidine in the Management of Acute Cardiogenic Pulmonary Edema, Safety and Efficacy
NCT06653244 ·Status: COMPLETED ·Phase: PHASE1
-
Effects of Dexmedetomidine on Postoperative Cognitive Dysfunction During One-lung Ventilation in Elder Patients
NCT02134093 ·Status: UNKNOWN ·Phase: PHASE4
-
A Comparision of Midazolam-dexmedetomidine With Dexmedetomidine Alone for Hemodynamic Stability and Quality of Sedation in Elderly Patients Under Spinal Anesthesia
NCT01979653 ·Status: WITHDRAWN ·Phase: NA
-
Comparison Between Dexmedetomidine and Propofol for Patients in the Intensive Care Unit After Abdominal Surgery
NCT02874768 ·Status: COMPLETED ·Phase: PHASE4
-
Transesophageal Echocardiographic Evaluation of the Effect of Dexmedetomidine Infusion as an Adjuvant to General Anesthesia on the Cardiac Function
NCT02300649 ·Status: COMPLETED ·Phase: NA
-
Do Increasing Preoperative Timing of Single Dexmedetomidine Dose Have an Effect on Stress Response of Laryngoscopy and Intubation?
NCT07165483 ·Status: RECRUITING ·Phase: NA